BDBM50201459 3-amino-N-(diaminomethylene)-5-o-tolylfuran-2-carboxamide::CHEMBL398144

SMILES: Cc1ccccc1-c1cc(N)c(o1)C(=O)NC(N)=N

InChI Key: InChIKey=RDDKUIQGVPCAIQ-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50201459   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sodium/hydrogen exchanger 1 (Homo sapiens (Human))	BDBM50201459 (3-amino-N-(diaminomethylene)-5-o-tolylfuran-2-carb...) Show SMILES Cc1ccccc1-c1cc(N)c(o1)C(=O)NC(N)=N Show InChI InChI=1S/C13H14N4O2/c1-7-4-2-3-5-8(7)10-6-9(14)11(19-10)12(18)17-13(15)16/h2-6H,14H2,1H3,(H4,15,16,17,18)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	240	n/a	n/a	n/a	n/a	n/a	n/a
Korea Research Institute of Chemical Technology Curated by ChEMBL					Assay Description Inhibition of human NHE1 expressed in PS120 cells				Bioorg Med Chem Lett 17: 1291-5 (2007) Article DOI: 10.1016/j.bmcl.2006.12.012 BindingDB Entry DOI: 10.7270/Q2MW2GS1
					More data for this Ligand-Target Pair