BDBM50201461 CHEMBL233778::N-(diaminomethylene)-5-(2,5-dichlorophenyl)-3-(methylamino)furan-2-carboxamide

SMILES: CNc1cc(oc1C(=O)NC(N)=N)-c1cc(Cl)ccc1Cl

InChI Key: InChIKey=QYNMFTTULPYKMA-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50201461   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sodium/hydrogen exchanger 1 (Homo sapiens (Human))	BDBM50201461 (CHEMBL233778 | N-(diaminomethylene)-5-(2,5-dichlor...) Show SMILES CNc1cc(oc1C(=O)NC(N)=N)-c1cc(Cl)ccc1Cl Show InChI InChI=1S/C13H12Cl2N4O2/c1-18-9-5-10(7-4-6(14)2-3-8(7)15)21-11(9)12(20)19-13(16)17/h2-5,18H,1H3,(H4,16,17,19,20)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	96	n/a	n/a	n/a	n/a	n/a	n/a
Korea Research Institute of Chemical Technology Curated by ChEMBL					Assay Description Inhibition of human NHE1 expressed in PS120 cells				Bioorg Med Chem Lett 17: 1291-5 (2007) Article DOI: 10.1016/j.bmcl.2006.12.012 BindingDB Entry DOI: 10.7270/Q2MW2GS1
					More data for this Ligand-Target Pair