BDBM50201468 5-(3-chlorophenyl)-N-(diaminomethylene)-3-(piperidin-1-yl)furan-2-carboxamide::CHEMBL233780

SMILES: NC(=N)NC(=O)c1oc(cc1N1CCCCC1)-c1cccc(Cl)c1

InChI Key: InChIKey=WQNUBLXCGYGAMW-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50201468   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sodium/hydrogen exchanger 1 (Homo sapiens (Human))	BDBM50201468 (5-(3-chlorophenyl)-N-(diaminomethylene)-3-(piperid...) Show SMILES NC(=N)NC(=O)c1oc(cc1N1CCCCC1)-c1cccc(Cl)c1 Show InChI InChI=1S/C17H19ClN4O2/c18-12-6-4-5-11(9-12)14-10-13(22-7-2-1-3-8-22)15(24-14)16(23)21-17(19)20/h4-6,9-10H,1-3,7-8H2,(H4,19,20,21,23)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.60E+4	n/a	n/a	n/a	n/a	n/a	n/a
Korea Research Institute of Chemical Technology Curated by ChEMBL					Assay Description Inhibition of human NHE1 expressed in PS120 cells				Bioorg Med Chem Lett 17: 1291-5 (2007) Article DOI: 10.1016/j.bmcl.2006.12.012 BindingDB Entry DOI: 10.7270/Q2MW2GS1
					More data for this Ligand-Target Pair