BDBM50201473 5-(5-chloro-2-methoxyphenyl)-N-(diaminomethylene)-3-(N-methylacetamido)furan-2-carboxamide::CHEMBL232180

SMILES: COc1ccc(Cl)cc1-c1cc(N(C)C(C)=O)c(o1)C(=O)NC(N)=N

InChI Key: InChIKey=CBYAATLHSVOXMP-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50201473   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sodium/hydrogen exchanger 1 (Homo sapiens (Human))	BDBM50201473 (5-(5-chloro-2-methoxyphenyl)-N-(diaminomethylene)-...) Show SMILES COc1ccc(Cl)cc1-c1cc(N(C)C(C)=O)c(o1)C(=O)NC(N)=N Show InChI InChI=1S/C16H17ClN4O4/c1-8(22)21(2)11-7-13(25-14(11)15(23)20-16(18)19)10-6-9(17)4-5-12(10)24-3/h4-7H,1-3H3,(H4,18,19,20,23)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.30E+4	n/a	n/a	n/a	n/a	n/a	n/a
Korea Research Institute of Chemical Technology Curated by ChEMBL					Assay Description Inhibition of human NHE1 expressed in PS120 cells				Bioorg Med Chem Lett 17: 1291-5 (2007) Article DOI: 10.1016/j.bmcl.2006.12.012 BindingDB Entry DOI: 10.7270/Q2MW2GS1
					More data for this Ligand-Target Pair