BDBM50201477 3-acetamido-5-(3-chlorophenyl)-N-(diaminomethylene)furan-2-carboxamide::CHEMBL443584

SMILES: CC(=O)Nc1cc(oc1C(=O)NC(N)=N)-c1cccc(Cl)c1

InChI Key: InChIKey=KYINPQSYYRMEPV-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50201477   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sodium/hydrogen exchanger 1 (Homo sapiens (Human))	BDBM50201477 (3-acetamido-5-(3-chlorophenyl)-N-(diaminomethylene...) Show SMILES CC(=O)Nc1cc(oc1C(=O)NC(N)=N)-c1cccc(Cl)c1 Show InChI InChI=1S/C14H13ClN4O3/c1-7(20)18-10-6-11(8-3-2-4-9(15)5-8)22-12(10)13(21)19-14(16)17/h2-6H,1H3,(H,18,20)(H4,16,17,19,21)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.40E+4	n/a	n/a	n/a	n/a	n/a	n/a
Korea Research Institute of Chemical Technology Curated by ChEMBL					Assay Description Inhibition of human NHE1 expressed in PS120 cells				Bioorg Med Chem Lett 17: 1291-5 (2007) Article DOI: 10.1016/j.bmcl.2006.12.012 BindingDB Entry DOI: 10.7270/Q2MW2GS1
					More data for this Ligand-Target Pair