BDBM50201574 CHEMBL3895853

SMILES: CN(C(=O)Cn1cc(nn1)-c1ccc(cc1)-n1ccnc1C)c1cccc(Cl)c1Cl

InChI Key: InChIKey=RBSGOJXGJTVMRX-UHFFFAOYSA-N

Data: 2 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50201574   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Probable G-protein coupled receptor 142 (Homo sapiens (Human))	BDBM50201574 (CHEMBL3895853) Show SMILES CN(C(=O)Cn1cc(nn1)-c1ccc(cc1)-n1ccnc1C)c1cccc(Cl)c1Cl Show InChI InChI=1S/C21H18Cl2N6O/c1-14-24-10-11-29(14)16-8-6-15(7-9-16)18-12-28(26-25-18)13-20(30)27(2)19-5-3-4-17(22)21(19)23/h3-12H,13H2,1-2H3	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	5.00E+3	n/a	n/a	n/a	n/a
Merck& Co. Curated by ChEMBL					Assay Description Agonist activity at human GPR142 expressed in CHO cells measured for 3 to 5 mins by Fluo-4AM dye-based FLIPR assay				ACS Med Chem Lett 7: 1107-1111 (2016) Article DOI: 10.1021/acsmedchemlett.6b00314 BindingDB Entry DOI: 10.7270/Q2ZC84V0
					More data for this Ligand-Target Pair
Probable G-protein coupled receptor 142 (Mus musculus)	BDBM50201574 (CHEMBL3895853) Show SMILES CN(C(=O)Cn1cc(nn1)-c1ccc(cc1)-n1ccnc1C)c1cccc(Cl)c1Cl Show InChI InChI=1S/C21H18Cl2N6O/c1-14-24-10-11-29(14)16-8-6-15(7-9-16)18-12-28(26-25-18)13-20(30)27(2)19-5-3-4-17(22)21(19)23/h3-12H,13H2,1-2H3	KEGG UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	>2.00E+4	n/a	n/a	n/a	n/a
Merck& Co. Curated by ChEMBL					Assay Description Agonist activity at mouse GPR142 expressed in CHO cells measured for 3 to 5 mins by Fluo-4AM dye-based FLIPR assay				ACS Med Chem Lett 7: 1107-1111 (2016) Article DOI: 10.1021/acsmedchemlett.6b00314 BindingDB Entry DOI: 10.7270/Q2ZC84V0
					More data for this Ligand-Target Pair