BDBM50201580 CHEMBL3923863

SMILES: Cc1nccn1-c1ccc(cc1)-c1cn(nn1)C(C)(C)C(=O)Nc1cccc(Cl)c1Cl

InChI Key: InChIKey=WXJZLQMCWDHDLZ-UHFFFAOYSA-N

Data: 2 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50201580   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Probable G-protein coupled receptor 142 (Mus musculus)	BDBM50201580 (CHEMBL3923863) Show SMILES Cc1nccn1-c1ccc(cc1)-c1cn(nn1)C(C)(C)C(=O)Nc1cccc(Cl)c1Cl Show InChI InChI=1S/C22H20Cl2N6O/c1-14-25-11-12-29(14)16-9-7-15(8-10-16)19-13-30(28-27-19)22(2,3)21(31)26-18-6-4-5-17(23)20(18)24/h4-13H,1-3H3,(H,26,31)	KEGG UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	801	n/a	n/a	n/a	n/a
Merck& Co. Curated by ChEMBL					Assay Description Agonist activity at mouse GPR142 expressed in CHO cells measured for 3 to 5 mins by Fluo-4AM dye-based FLIPR assay				ACS Med Chem Lett 7: 1107-1111 (2016) Article DOI: 10.1021/acsmedchemlett.6b00314 BindingDB Entry DOI: 10.7270/Q2ZC84V0
					More data for this Ligand-Target Pair
Probable G-protein coupled receptor 142 (Homo sapiens (Human))	BDBM50201580 (CHEMBL3923863) Show SMILES Cc1nccn1-c1ccc(cc1)-c1cn(nn1)C(C)(C)C(=O)Nc1cccc(Cl)c1Cl Show InChI InChI=1S/C22H20Cl2N6O/c1-14-25-11-12-29(14)16-9-7-15(8-10-16)19-13-30(28-27-19)22(2,3)21(31)26-18-6-4-5-17(23)20(18)24/h4-13H,1-3H3,(H,26,31)	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	>2.00E+4	n/a	n/a	n/a	n/a
Merck& Co. Curated by ChEMBL					Assay Description Agonist activity at human GPR142 expressed in CHO cells measured for 3 to 5 mins by Fluo-4AM dye-based FLIPR assay				ACS Med Chem Lett 7: 1107-1111 (2016) Article DOI: 10.1021/acsmedchemlett.6b00314 BindingDB Entry DOI: 10.7270/Q2ZC84V0
					More data for this Ligand-Target Pair