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SMILES: Cn1cc(O)nc1NC(=O)Nc1ccncc1Cl

InChI Key: InChIKey=BJUXAJOTCBHMPO-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50201674   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Metabotropic glutamate receptor 5


(Homo sapiens (Human))		BDBM50201674
PNG
((E)-1-(2-chloropyridin-4-yl)-3-(1-methyl-4-oxoimid...)
Show SMILES Cn1cc(O)nc1NC(=O)Nc1ccncc1Cl
Show InChI InChI=1S/C10H10ClN5O2/c1-16-5-8(17)14-9(16)15-10(18)13-7-2-3-12-4-6(7)11/h2-5,17H,1H3,(H2,12,13,14,15,18)
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Article
PubMed
n/an/a 663n/an/an/an/an/an/a



F. Hoffmann-La Roche Ltd

Curated by ChEMBL


Assay Description
Displacement of [3H]MPEP from mGlu5 receptor

Bioorg Med Chem Lett 17: 1307-11 (2007)


Article DOI: 10.1016/j.bmcl.2006.12.033
BindingDB Entry DOI: 10.7270/Q2V987R8
More data for this
Ligand-Target Pair