BindingDB PrimarySearch

BDBM50202292 11-valeryloxynoraporphine::CHEMBL403550::Pentanoic acid (R)-6-propyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinolin-11-yl ester

SMILES: CCCCC(=O)Oc1cccc2C[C@H]3N(CCC)CCc4cccc(c34)-c12

InChI Key: InChIKey=JGCVBGVDWQJTDF-HXUWFJFHSA-N

Data: 8 KI

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50202292
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
D(1A) dopamine receptor (Homo sapiens (Human))	BDBM50202292 (11-valeryloxynoraporphine \| CHEMBL403550 \| Pentano...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	23	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Displacement of [3H]8OH-DPAT from human dopamine D1 receptor expressed in HEK293 cells				Bioorg Med Chem 16: 8335-8 (2008) Article DOI: 10.1016/j.bmc.2008.08.056 BindingDB Entry DOI: 10.7270/Q2Q52PG5
Chinese Academy of Sciences Curated by ChEMBL					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50202292 (11-valeryloxynoraporphine \| CHEMBL403550 \| Pentano...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	34	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Displacement of [3H]raclopride from rat dopamine D2 receptor				J Med Chem 50: 171-81 (2007) Article DOI: 10.1021/jm060959i BindingDB Entry DOI: 10.7270/Q22J6CPJ
Chinese Academy of Sciences Curated by ChEMBL					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Homo sapiens (Human))	BDBM50202292 (11-valeryloxynoraporphine \| CHEMBL403550 \| Pentano...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	92	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Displacement of [3H]Spiperone from human 5HT2A receptor expressed in HEK293 cells				Bioorg Med Chem 16: 8335-8 (2008) Article DOI: 10.1016/j.bmc.2008.08.056 BindingDB Entry DOI: 10.7270/Q2Q52PG5
Chinese Academy of Sciences Curated by ChEMBL					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50202292 (11-valeryloxynoraporphine \| CHEMBL403550 \| Pentano...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	340	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Harvard Medical School Curated by ChEMBL					Assay Description Displacement of [3H]nemonapride from dopamine D2 receptor in rat forebrain				Bioorg Med Chem Lett 19: 51-3 (2008) Article DOI: 10.1016/j.bmcl.2008.11.025 BindingDB Entry DOI: 10.7270/Q26W99XP
Harvard Medical School Curated by ChEMBL					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50202292 (11-valeryloxynoraporphine \| CHEMBL403550 \| Pentano...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Displacement of [3H]SCH23390 from rat 5HT1A receptor expressed in CHO cells				Bioorg Med Chem 16: 8335-8 (2008) Article DOI: 10.1016/j.bmc.2008.08.056 BindingDB Entry DOI: 10.7270/Q2Q52PG5
Chinese Academy of Sciences Curated by ChEMBL					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50202292 (11-valeryloxynoraporphine \| CHEMBL403550 \| Pentano...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Displacement of [3H]ketanserin from human dopamine D2 receptor expressed in HEK293 cells				Bioorg Med Chem 16: 8335-8 (2008) Article DOI: 10.1016/j.bmc.2008.08.056 BindingDB Entry DOI: 10.7270/Q2Q52PG5
Chinese Academy of Sciences Curated by ChEMBL					More data for this Ligand-Target Pair
D(1A) dopamine receptor (RAT)	BDBM50202292 (11-valeryloxynoraporphine \| CHEMBL403550 \| Pentano...) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Displacement of [3H]SCH-23390 from rat dopamine D1 receptor				J Med Chem 50: 171-81 (2007) Article DOI: 10.1021/jm060959i BindingDB Entry DOI: 10.7270/Q22J6CPJ
Chinese Academy of Sciences Curated by ChEMBL					More data for this Ligand-Target Pair
D(1A) dopamine receptor (RAT)	BDBM50202292 (11-valeryloxynoraporphine \| CHEMBL403550 \| Pentano...) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Harvard Medical School Curated by ChEMBL					Assay Description Displacement of [3H]SCH23390 from dopamine D1 receptor in rat forebrain				Bioorg Med Chem Lett 19: 51-3 (2008) Article DOI: 10.1016/j.bmcl.2008.11.025 BindingDB Entry DOI: 10.7270/Q26W99XP
Harvard Medical School Curated by ChEMBL					More data for this Ligand-Target Pair