BDBM50202316 1-ethyl-2,3,12,12a-tetrahydro-1H-7-oxa-1-aza-pleiaden-10-ol::CHEMBL154468

SMILES: CCN1CCc2cccc3Oc4ccc(O)cc4CC1c23

InChI Key: InChIKey=WDBUJQKFRINDKP-UHFFFAOYSA-N

Data: 4 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50202316   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
D(1A) dopamine receptor (RAT)	BDBM50202316 (1-ethyl-2,3,12,12a-tetrahydro-1H-7-oxa-1-aza-pleia...) Show SMILES CCN1CCc2cccc3Oc4ccc(O)cc4CC1c23 Show InChI InChI=1S/C18H19NO2/c1-2-19-9-8-12-4-3-5-17-18(12)15(19)11-13-10-14(20)6-7-16(13)21-17/h3-7,10,15,20H,2,8-9,11H2,1H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	6.76E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Camerino Curated by ChEMBL					Assay Description Binding Affinity was determined against Dopamine receptor D1 in rat striatal membranes using [3H]- SCH 23390 radioligand.				J Med Chem 43: 599-608 (2000) Article DOI: 10.1021/jm991034o BindingDB Entry DOI: 10.7270/Q2X35161
					More data for this Ligand-Target Pair
D(1A) dopamine receptor (RAT)	BDBM50202316 (1-ethyl-2,3,12,12a-tetrahydro-1H-7-oxa-1-aza-pleia...) Show SMILES CCN1CCc2cccc3Oc4ccc(O)cc4CC1c23 Show InChI InChI=1S/C18H19NO2/c1-2-19-9-8-12-4-3-5-17-18(12)15(19)11-13-10-14(20)6-7-16(13)21-17/h3-7,10,15,20H,2,8-9,11H2,1H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	6.80E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Displacement of [3H]SCH-23390 from rat dopamine D1 receptor				J Med Chem 50: 171-81 (2007) Article DOI: 10.1021/jm060959i BindingDB Entry DOI: 10.7270/Q22J6CPJ
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50202316 (1-ethyl-2,3,12,12a-tetrahydro-1H-7-oxa-1-aza-pleia...) Show SMILES CCN1CCc2cccc3Oc4ccc(O)cc4CC1c23 Show InChI InChI=1S/C18H19NO2/c1-2-19-9-8-12-4-3-5-17-18(12)15(19)11-13-10-14(20)6-7-16(13)21-17/h3-7,10,15,20H,2,8-9,11H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	<1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Camerino Curated by ChEMBL					Assay Description Binding Affinity was determined against Dopamine receptor D2 in rat striatal membranes using [3H]- spiperone radioligand.				J Med Chem 43: 599-608 (2000) Article DOI: 10.1021/jm991034o BindingDB Entry DOI: 10.7270/Q2X35161
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50202316 (1-ethyl-2,3,12,12a-tetrahydro-1H-7-oxa-1-aza-pleia...) Show SMILES CCN1CCc2cccc3Oc4ccc(O)cc4CC1c23 Show InChI InChI=1S/C18H19NO2/c1-2-19-9-8-12-4-3-5-17-18(12)15(19)11-13-10-14(20)6-7-16(13)21-17/h3-7,10,15,20H,2,8-9,11H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Displacement of [3H]raclopride from rat dopamine D2 receptor				J Med Chem 50: 171-81 (2007) Article DOI: 10.1021/jm060959i BindingDB Entry DOI: 10.7270/Q22J6CPJ
					More data for this Ligand-Target Pair