Found 4 hits for monomerid = 50202531 Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
cAMP-specific 3',5'-cyclic phosphodiesterase 4C isoform 1
(Homo sapiens (Human)) | BDBM50202531
(9-cyclopentyl-5,6-dihydro-7-ethyl-3-(tert-butyl)-9...)Show InChI InChI=1S/C18H27N5/c1-5-14-13-10-11-22-16(19-20-17(22)18(2,3)4)15(13)23(21-14)12-8-6-7-9-12/h12H,5-11H2,1-4H3 | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 40 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development
Curated by ChEMBL
| Assay Description Inhibition of human recombinant PDE4C |
J Med Chem 50: 344-9 (2007)
Article DOI: 10.1021/jm060904g BindingDB Entry DOI: 10.7270/Q2K0753Z |
More data for this Ligand-Target Pair | |
cAMP-specific 3',5'-cyclic phosphodiesterase 4A
(Homo sapiens (Human)) | BDBM50202531
(9-cyclopentyl-5,6-dihydro-7-ethyl-3-(tert-butyl)-9...)Show InChI InChI=1S/C18H27N5/c1-5-14-13-10-11-22-16(19-20-17(22)18(2,3)4)15(13)23(21-14)12-8-6-7-9-12/h12H,5-11H2,1-4H3 | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 11 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development
Curated by ChEMBL
| Assay Description Inhibition of human recombinant PDE4A |
J Med Chem 50: 344-9 (2007)
Article DOI: 10.1021/jm060904g BindingDB Entry DOI: 10.7270/Q2K0753Z |
More data for this Ligand-Target Pair | |
cAMP-specific 3',5'-cyclic phosphodiesterase 4D
(Homo sapiens (Human)) | BDBM50202531
(9-cyclopentyl-5,6-dihydro-7-ethyl-3-(tert-butyl)-9...)Show InChI InChI=1S/C18H27N5/c1-5-14-13-10-11-22-16(19-20-17(22)18(2,3)4)15(13)23(21-14)12-8-6-7-9-12/h12H,5-11H2,1-4H3 | PDB
KEGG
UniProtKB/SwissProt UniProtKB/TrEMBL
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 9 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development
Curated by ChEMBL
| Assay Description Inhibition of human recombinant PDE4D |
J Med Chem 50: 344-9 (2007)
Article DOI: 10.1021/jm060904g BindingDB Entry DOI: 10.7270/Q2K0753Z |
More data for this Ligand-Target Pair | |
cAMP-specific 3',5'-cyclic phosphodiesterase 4B
(Homo sapiens (Human)) | BDBM50202531
(9-cyclopentyl-5,6-dihydro-7-ethyl-3-(tert-butyl)-9...)Show InChI InChI=1S/C18H27N5/c1-5-14-13-10-11-22-16(19-20-17(22)18(2,3)4)15(13)23(21-14)12-8-6-7-9-12/h12H,5-11H2,1-4H3 | PDB
UniProtKB/SwissProt UniProtKB/TrEMBL
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 8 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development
Curated by ChEMBL
| Assay Description Inhibition of human recombinant PDE4B |
J Med Chem 50: 344-9 (2007)
Article DOI: 10.1021/jm060904g BindingDB Entry DOI: 10.7270/Q2K0753Z |
More data for this Ligand-Target Pair | |