BDBM50202837 CHEMBL3941751

SMILES: Cc1ccc(cc1)S([O-])(=O)=O.C[n+]1ccc2c3c(nc4ccccc24)-c2ccccc2-c13

InChI Key: InChIKey=RTEWVPHRSLJLPZ-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50202837   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
DNA topoisomerase 1 (Homo sapiens (Human))	BDBM50202837 (CHEMBL3941751) Show SMILES Cc1ccc(cc1)S([O-])(=O)=O.C[n+]1ccc2c3c(nc4ccccc24)-c2ccccc2-c13 Show InChI InChI=1S/C19H13N2/c1-21-11-10-13-12-6-4-5-9-16(12)20-18-14-7-2-3-8-15(14)19(21)17(13)18/h2-11H,1H3/q+1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.58E+3	n/a	n/a	n/a	n/a	n/a	n/a
Southern Research Institute Curated by ChEMBL					Assay Description Inhibition of human DNA topoisomerase 1 using pHOT1 as substrate after 30 mins by agarose gel electrophoresis				Bioorg Med Chem 24: 6119-6130 (2016) Article DOI: 10.1016/j.bmc.2016.02.028 BindingDB Entry DOI: 10.7270/Q2BG2QZJ
					More data for this Ligand-Target Pair