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SMILES: CC(C)Oc1ccc2ccccc2c1CCCCN1CCN(CC(N2CCN(CC2)C(C)C)c2ccc(F)cc2)CC1

InChI Key: InChIKey=LXYNSRGSZRHNAF-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50202925   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Melanocortin receptor 4


(Homo sapiens (Human))		BDBM50202925
PNG
(1-(1-(4-fluorophenyl)-2-{4-[4-(2-isopropoxy-1-naph...)
Show SMILES CC(C)Oc1ccc2ccccc2c1CCCCN1CCN(CC(N2CCN(CC2)C(C)C)c2ccc(F)cc2)CC1 |w:23.24|
Show InChI InChI=1S/C36H51FN4O/c1-28(2)40-23-25-41(26-24-40)35(31-12-15-32(37)16-13-31)27-39-21-19-38(20-22-39)18-8-7-11-34-33-10-6-5-9-30(33)14-17-36(34)42-29(3)4/h5-6,9-10,12-17,28-29,35H,7-8,11,18-27H2,1-4H3
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Article
PubMed
n/an/a 22n/an/an/an/an/an/a



Taisho Pharmaceutical Co., Ltd

Curated by ChEMBL


Assay Description
Displacement of [125I]Nle4-D-Phe7-alpha-MSH from human MC4 receptor expressed in COS1 cells

Bioorg Med Chem 15: 1989-2005 (2007)


Article DOI: 10.1016/j.bmc.2006.12.039
BindingDB Entry DOI: 10.7270/Q2C53KHN
More data for this
Ligand-Target Pair