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SMILES: CC(C)N1CCN(CC1)C(CN1CCN(CCCc2ccccc2-c2ccc(cc2)N(C)C)CC1)c1ccc(F)cc1

InChI Key: InChIKey=QAHPGFWCLSTEMJ-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50202975   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Melanocortin receptor 4


(Homo sapiens (Human))		BDBM50202975
PNG
((+/-)-2'-(3-{4-[2-(4-fluorophenyl)-2-(4-isopropylp...)
Show SMILES CC(C)N1CCN(CC1)C(CN1CCN(CCCc2ccccc2-c2ccc(cc2)N(C)C)CC1)c1ccc(F)cc1 |w:9.10|
Show InChI InChI=1S/C36H50FN5/c1-29(2)41-24-26-42(27-25-41)36(32-11-15-33(37)16-12-32)28-40-22-20-39(21-23-40)19-7-9-30-8-5-6-10-35(30)31-13-17-34(18-14-31)38(3)4/h5-6,8,10-18,29,36H,7,9,19-28H2,1-4H3
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PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 92.5n/an/an/an/an/an/a



Taisho Pharmaceutical Co., Ltd

Curated by ChEMBL


Assay Description
Displacement of [125I]Nle4-D-Phe7-alpha-MSH from human MC4 receptor expressed in COS1 cells

Bioorg Med Chem 15: 1989-2005 (2007)


Article DOI: 10.1016/j.bmc.2006.12.039
BindingDB Entry DOI: 10.7270/Q2C53KHN
More data for this
Ligand-Target Pair