BDBM50203111 CHEMBL3968023

SMILES: [I-].C[n+]1ccc2c3c(nc4cc5OCOc5cc24)-c2ccccc2-c13

InChI Key: InChIKey=SQLDZTBBSNZSKZ-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50203111   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
DNA topoisomerase I (Topo I) (Homo sapiens (Human))	BDBM50203111 (CHEMBL3968023) Show SMILES [I-].C[n+]1ccc2c3c(nc4cc5OCOc5cc24)-c2ccccc2-c13 Show InChI InChI=1S/C20H13N2O2/c1-22-7-6-11-14-8-16-17(24-10-23-16)9-15(14)21-19-12-4-2-3-5-13(12)20(22)18(11)19/h2-9H,10H2,1H3/q+1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.02E+3	n/a	n/a	n/a	n/a	n/a	n/a
Southern Research Institute Curated by ChEMBL					Assay Description Inhibition of human DNA topoisomerase 1 using pHOT1 as substrate after 30 mins by agarose gel electrophoresis				Bioorg Med Chem 24: 6119-6130 (2016) Article DOI: 10.1016/j.bmc.2016.02.028 BindingDB Entry DOI: 10.7270/Q2BG2QZJ
					More data for this Ligand-Target Pair