BDBM50203428 CHEMBL3970276

SMILES: C[C@H](NC(=O)C(C)(C)C)[C@H](Oc1ccc2n(ncc2c1)-c1ccc(F)cc1)c1ccccc1

InChI Key: InChIKey=JZIVIKFFTCIHGU-BVZFJXPGSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50203428   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glucocorticoid receptor (Homo sapiens (Human))	BDBM50203428 (CHEMBL3970276) Show SMILES C[C@H](NC(=O)C(C)(C)C)[C@H](Oc1ccc2n(ncc2c1)-c1ccc(F)cc1)c1ccccc1 |r| Show InChI InChI=1S/C27H28FN3O2/c1-18(30-26(32)27(2,3)4)25(19-8-6-5-7-9-19)33-23-14-15-24-20(16-23)17-29-31(24)22-12-10-21(28)11-13-22/h5-18,25H,1-4H3,(H,30,32)/t18-,25-/m0/s1	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.660	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Agonist activity at glucocorticoid receptor in human ChaGoK1 cells assessed as inhibition of AP1-mediated transcriptional activity by measuring reduc...				Bioorg Med Chem Lett 26: 5741-5748 (2016) Article DOI: 10.1016/j.bmcl.2016.10.052 BindingDB Entry DOI: 10.7270/Q2NP26D1
					More data for this Ligand-Target Pair