BDBM50203978 CHEMBL233384::N-(4-(2-(2-chloro-4-(cyclopropylmethoxy)phenoxy)thiazol-5-yl)but-3-yn-2-yl)acetamide

SMILES: CC(NC(C)=O)C#Cc1cnc(Oc2ccc(OCC3CC3)cc2Cl)s1

InChI Key: InChIKey=ZHGFQYGTIFIGPF-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50203978   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Acetyl-CoA carboxylase 1 (ACC1) (Homo sapiens (Human))	BDBM50203978 (CHEMBL233384 | N-(4-(2-(2-chloro-4-(cyclopropylmet...) Show SMILES CC(NC(C)=O)C#Cc1cnc(Oc2ccc(OCC3CC3)cc2Cl)s1 |w:1.0| Show InChI InChI=1S/C19H19ClN2O3S/c1-12(22-13(2)23)3-7-16-10-21-19(26-16)25-18-8-6-15(9-17(18)20)24-11-14-4-5-14/h6,8-10,12,14H,4-5,11H2,1-2H3,(H,22,23)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibition of human recombinant ACC1				Bioorg Med Chem Lett 17: 1961-5 (2007) Article DOI: 10.1016/j.bmcl.2007.01.022 BindingDB Entry DOI: 10.7270/Q2W095KS
					More data for this Ligand-Target Pair
Acetyl-CoA carboxylase 2 (ACC2) (Homo sapiens (Human))	BDBM50203978 (CHEMBL233384 | N-(4-(2-(2-chloro-4-(cyclopropylmet...) Show SMILES CC(NC(C)=O)C#Cc1cnc(Oc2ccc(OCC3CC3)cc2Cl)s1 |w:1.0| Show InChI InChI=1S/C19H19ClN2O3S/c1-12(22-13(2)23)3-7-16-10-21-19(26-16)25-18-8-6-15(9-17(18)20)24-11-14-4-5-14/h6,8-10,12,14H,4-5,11H2,1-2H3,(H,22,23)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibition of human recombinant ACC2				Bioorg Med Chem Lett 17: 1961-5 (2007) Article DOI: 10.1016/j.bmcl.2007.01.022 BindingDB Entry DOI: 10.7270/Q2W095KS
					More data for this Ligand-Target Pair