BDBM50205236 3-(2'-deoxy-beta-D-ribofuranosyl)-6-(3-fluoroethoxyphenyl)-2,3-dihydrofuro[2,3-d]pyrimidin-2-one::CHEMBL219733

SMILES: OC[C@H]1O[C@H](C[C@@H]1O)n1cc2cc(oc2nc1=O)-c1cccc(OCCF)c1

InChI Key: InChIKey=KQLFOIAXOLHCMZ-USXIJHARSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50205236   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Thymidine kinase, cytosolic (Homo sapiens (Human))	BDBM50205236 (3-(2'-deoxy-beta-D-ribofuranosyl)-6-(3-fluoroethox...) Show SMILES OC[C@H]1O[C@H](C[C@@H]1O)n1cc2cc(oc2nc1=O)-c1cccc(OCCF)c1 Show InChI InChI=1S/C19H19FN2O6/c20-4-5-26-13-3-1-2-11(6-13)15-7-12-9-22(19(25)21-18(12)28-15)17-8-14(24)16(10-23)27-17/h1-3,6-7,9,14,16-17,23-24H,4-5,8,10H2/t14-,16+,17+/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>5.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
K.U. Leuven Curated by ChEMBL					Assay Description Inhibition of recombinant cytosolic TK-1 assessed as [CH3-H3]dThd phosphorylation				J Med Chem 50: 1041-9 (2007) Article DOI: 10.1021/jm060964m BindingDB Entry DOI: 10.7270/Q2833RQS
					More data for this Ligand-Target Pair
Thymidine kinase (Human herpesvirus 1 (strain SC16) (HHV-1) (Human h...)	BDBM50205236 (3-(2'-deoxy-beta-D-ribofuranosyl)-6-(3-fluoroethox...) Show SMILES OC[C@H]1O[C@H](C[C@@H]1O)n1cc2cc(oc2nc1=O)-c1cccc(OCCF)c1 Show InChI InChI=1S/C19H19FN2O6/c20-4-5-26-13-3-1-2-11(6-13)15-7-12-9-22(19(25)21-18(12)28-15)17-8-14(24)16(10-23)27-17/h1-3,6-7,9,14,16-17,23-24H,4-5,8,10H2/t14-,16+,17+/m0/s1	PDB MMDB B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>5.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
K.U. Leuven Curated by ChEMBL					Assay Description Inhibition of recombinant HSV-1 TK assessed as [CH3-H3]dThd phosphorylation				J Med Chem 50: 1041-9 (2007) Article DOI: 10.1021/jm060964m BindingDB Entry DOI: 10.7270/Q2833RQS
					More data for this Ligand-Target Pair