Found 6 hits for monomerid = 50206066 Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kcal/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Nitric oxide synthase, inducible
(Rattus norvegicus) | BDBM50206066
(CHEMBL233653 | N-(2-{1-[2-(3H-imidazol-4-yl)-ethyl...)Show SMILES NC(=Nc1ccc2nc(NC3CCN(CCc4cnc[nH]4)CC3)sc2c1)c1cccs1 |w:2.2| Show InChI InChI=1S/C22H25N7S2/c23-21(19-2-1-11-30-19)26-16-3-4-18-20(12-16)31-22(28-18)27-15-5-8-29(9-6-15)10-7-17-13-24-14-25-17/h1-4,11-15H,5-10H2,(H2,23,26)(H,24,25)(H,27,28) | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet 
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 2.60E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
NeurAxon Inc.
Curated by ChEMBL
| Assay Description
Inhibition of rat inducible NOS activity |
Bioorg Med Chem Lett 17: 2540-4 (2007)
Article DOI: 10.1016/j.bmcl.2007.02.011
BindingDB Entry DOI: 10.7270/Q2WM1F6B |
More data for this
Ligand-Target Pair | |
Nitric oxide synthase, inducible
(Homo sapiens (Human)) | BDBM50206066
(CHEMBL233653 | N-(2-{1-[2-(3H-imidazol-4-yl)-ethyl...)Show SMILES NC(=Nc1ccc2nc(NC3CCN(CCc4cnc[nH]4)CC3)sc2c1)c1cccs1 |w:2.2| Show InChI InChI=1S/C22H25N7S2/c23-21(19-2-1-11-30-19)26-16-3-4-18-20(12-16)31-22(28-18)27-15-5-8-29(9-6-15)10-7-17-13-24-14-25-17/h1-4,11-15H,5-10H2,(H2,23,26)(H,24,25)(H,27,28) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 6.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
NeurAxon Inc.
Curated by ChEMBL
| Assay Description
Inhibition of human inducible NOS activity |
Bioorg Med Chem Lett 17: 2540-4 (2007)
Article DOI: 10.1016/j.bmcl.2007.02.011
BindingDB Entry DOI: 10.7270/Q2WM1F6B |
More data for this
Ligand-Target Pair | |
Nitric oxide synthase, brain
(Rattus norvegicus (rat)) | BDBM50206066
(CHEMBL233653 | N-(2-{1-[2-(3H-imidazol-4-yl)-ethyl...)Show SMILES NC(=Nc1ccc2nc(NC3CCN(CCc4cnc[nH]4)CC3)sc2c1)c1cccs1 |w:2.2| Show InChI InChI=1S/C22H25N7S2/c23-21(19-2-1-11-30-19)26-16-3-4-18-20(12-16)31-22(28-18)27-15-5-8-29(9-6-15)10-7-17-13-24-14-25-17/h1-4,11-15H,5-10H2,(H2,23,26)(H,24,25)(H,27,28) | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 4.80E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
NeurAxon Inc.
Curated by ChEMBL
| Assay Description
Inhibition of rat neuronal NOS activity |
Bioorg Med Chem Lett 17: 2540-4 (2007)
Article DOI: 10.1016/j.bmcl.2007.02.011
BindingDB Entry DOI: 10.7270/Q2WM1F6B |
More data for this
Ligand-Target Pair | |
Nitric oxide synthase, brain
(Homo sapiens (Human)) | BDBM50206066
(CHEMBL233653 | N-(2-{1-[2-(3H-imidazol-4-yl)-ethyl...)Show SMILES NC(=Nc1ccc2nc(NC3CCN(CCc4cnc[nH]4)CC3)sc2c1)c1cccs1 |w:2.2| Show InChI InChI=1S/C22H25N7S2/c23-21(19-2-1-11-30-19)26-16-3-4-18-20(12-16)31-22(28-18)27-15-5-8-29(9-6-15)10-7-17-13-24-14-25-17/h1-4,11-15H,5-10H2,(H2,23,26)(H,24,25)(H,27,28) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 300 | n/a | n/a | n/a | n/a | n/a | n/a |
NeurAxon Inc.
Curated by ChEMBL
| Assay Description
Inhibition of human neuronal NOS activity |
Bioorg Med Chem Lett 17: 2540-4 (2007)
Article DOI: 10.1016/j.bmcl.2007.02.011
BindingDB Entry DOI: 10.7270/Q2WM1F6B |
More data for this
Ligand-Target Pair | |
Nitric oxide synthase, endothelial
(Rattus norvegicus) | BDBM50206066
(CHEMBL233653 | N-(2-{1-[2-(3H-imidazol-4-yl)-ethyl...)Show SMILES NC(=Nc1ccc2nc(NC3CCN(CCc4cnc[nH]4)CC3)sc2c1)c1cccs1 |w:2.2| Show InChI InChI=1S/C22H25N7S2/c23-21(19-2-1-11-30-19)26-16-3-4-18-20(12-16)31-22(28-18)27-15-5-8-29(9-6-15)10-7-17-13-24-14-25-17/h1-4,11-15H,5-10H2,(H2,23,26)(H,24,25)(H,27,28) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 4.60E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
NeurAxon Inc.
Curated by ChEMBL
| Assay Description
Inhibition of rat endothelial NOS activity |
Bioorg Med Chem Lett 17: 2540-4 (2007)
Article DOI: 10.1016/j.bmcl.2007.02.011
BindingDB Entry DOI: 10.7270/Q2WM1F6B |
More data for this
Ligand-Target Pair | |
Nitric oxide synthase, endothelial
(Homo sapiens (Human)) | BDBM50206066
(CHEMBL233653 | N-(2-{1-[2-(3H-imidazol-4-yl)-ethyl...)Show SMILES NC(=Nc1ccc2nc(NC3CCN(CCc4cnc[nH]4)CC3)sc2c1)c1cccs1 |w:2.2| Show InChI InChI=1S/C22H25N7S2/c23-21(19-2-1-11-30-19)26-16-3-4-18-20(12-16)31-22(28-18)27-15-5-8-29(9-6-15)10-7-17-13-24-14-25-17/h1-4,11-15H,5-10H2,(H2,23,26)(H,24,25)(H,27,28) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 700 | n/a | n/a | n/a | n/a | n/a | n/a |
NeurAxon Inc.
Curated by ChEMBL
| Assay Description
Inhibition of human endothelial NOS activity |
Bioorg Med Chem Lett 17: 2540-4 (2007)
Article DOI: 10.1016/j.bmcl.2007.02.011
BindingDB Entry DOI: 10.7270/Q2WM1F6B |
More data for this
Ligand-Target Pair | |
Search and Browse
