BDBM50206348 1-(cyclohexylcarbonyl)-N-{4-[4-(2-methoxyphenyl)piperazin-1-yl]butyl}-L-prolinamide::CHEMBL232035

SMILES: COc1ccccc1N1CCN(CCCC[C@@H]2CCCN2C(=O)C2CCCCC2)CC1

InChI Key: InChIKey=KVMZOTTULOREGX-HSZRJFAPSA-N

Data: 3 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50206348   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50206348 (1-(cyclohexylcarbonyl)-N-{4-[4-(2-methoxyphenyl)pi...) Show SMILES COc1ccccc1N1CCN(CCCC[C@@H]2CCCN2C(=O)C2CCCCC2)CC1 Show InChI InChI=1S/C26H41N3O2/c1-31-25-15-6-5-14-24(25)28-20-18-27(19-21-28)16-8-7-12-23-13-9-17-29(23)26(30)22-10-3-2-4-11-22/h5-6,14-15,22-23H,2-4,7-13,16-21H2,1H3/t23-/m1/s1	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	19	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Université Montpellier I et II Curated by ChEMBL					Assay Description Displacement of [3H]8-OH-DPAT from serotonin 5HT1A receptor in rat brain hippocampus				Bioorg Med Chem 15: 2907-19 (2007) Article DOI: 10.1016/j.bmc.2007.02.018 BindingDB Entry DOI: 10.7270/Q20G3JTZ
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Rattus norvegicus (rat))	BDBM50206348 (1-(cyclohexylcarbonyl)-N-{4-[4-(2-methoxyphenyl)pi...) Show SMILES COc1ccccc1N1CCN(CCCC[C@@H]2CCCN2C(=O)C2CCCCC2)CC1 Show InChI InChI=1S/C26H41N3O2/c1-31-25-15-6-5-14-24(25)28-20-18-27(19-21-28)16-8-7-12-23-13-9-17-29(23)26(30)22-10-3-2-4-11-22/h5-6,14-15,22-23H,2-4,7-13,16-21H2,1H3/t23-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	990	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Université Montpellier I et II Curated by ChEMBL					Assay Description Displacement of [3H]ketanserin from serotonin 5HT2A receptor in rat brain cortex				Bioorg Med Chem 15: 2907-19 (2007) Article DOI: 10.1016/j.bmc.2007.02.018 BindingDB Entry DOI: 10.7270/Q20G3JTZ
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50206348 (1-(cyclohexylcarbonyl)-N-{4-[4-(2-methoxyphenyl)pi...) Show SMILES COc1ccccc1N1CCN(CCCC[C@@H]2CCCN2C(=O)C2CCCCC2)CC1 Show InChI InChI=1S/C26H41N3O2/c1-31-25-15-6-5-14-24(25)28-20-18-27(19-21-28)16-8-7-12-23-13-9-17-29(23)26(30)22-10-3-2-4-11-22/h5-6,14-15,22-23H,2-4,7-13,16-21H2,1H3/t23-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3.60E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Université Montpellier I et II Curated by ChEMBL					Assay Description Displacement of [3H]spiperone from dopaminergic D2 receptor in rat striatal membrane				Bioorg Med Chem 15: 2907-19 (2007) Article DOI: 10.1016/j.bmc.2007.02.018 BindingDB Entry DOI: 10.7270/Q20G3JTZ
					More data for this Ligand-Target Pair