BDBM50206350 CHEMBL390037::N-((S)-1-{4-[4-(3-chlorophenyl)piperazin-1-yl]butyl}pyrrolidin-2,5-dion-3-yl)-2-(bicyclo[2.2.1]heptan-2-yl)acetamide

SMILES: Clc1cccc(c1)N1CCN(CCCCN2C(=O)C[C@H](NC(=O)CC3CC4CCC3C4)C2=O)CC1

InChI Key: InChIKey=XHIDRVCCMYQHQX-HFHBMHTISA-N

Data: 3 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50206350   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5-hydroxytryptamine receptor 2A (Rattus norvegicus (rat))	BDBM50206350 (CHEMBL390037 | N-((S)-1-{4-[4-(3-chlorophenyl)pipe...) Show SMILES Clc1cccc(c1)N1CCN(CCCCN2C(=O)C[C@H](NC(=O)CC3CC4CCC3C4)C2=O)CC1 |w:24.24,29.29,26.27,TEB:23:24:27.28:30| Show InChI InChI=1S/C27H37ClN4O3/c28-22-4-3-5-23(17-22)31-12-10-30(11-13-31)8-1-2-9-32-26(34)18-24(27(32)35)29-25(33)16-21-15-19-6-7-20(21)14-19/h3-5,17,19-21,24H,1-2,6-16,18H2,(H,29,33)/t19?,20?,21?,24-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	4.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Université Montpellier I et II Curated by ChEMBL					Assay Description Displacement of [3H]ketanserin from serotonin 5HT2A receptor in rat brain cortex				Bioorg Med Chem 15: 2907-19 (2007) Article DOI: 10.1016/j.bmc.2007.02.018 BindingDB Entry DOI: 10.7270/Q20G3JTZ
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50206350 (CHEMBL390037 | N-((S)-1-{4-[4-(3-chlorophenyl)pipe...) Show SMILES Clc1cccc(c1)N1CCN(CCCCN2C(=O)C[C@H](NC(=O)CC3CC4CCC3C4)C2=O)CC1 |w:24.24,29.29,26.27,TEB:23:24:27.28:30| Show InChI InChI=1S/C27H37ClN4O3/c28-22-4-3-5-23(17-22)31-12-10-30(11-13-31)8-1-2-9-32-26(34)18-24(27(32)35)29-25(33)16-21-15-19-6-7-20(21)14-19/h3-5,17,19-21,24H,1-2,6-16,18H2,(H,29,33)/t19?,20?,21?,24-/m0/s1	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	21	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Université Montpellier I et II Curated by ChEMBL					Assay Description Displacement of [3H]8-OH-DPAT from serotonin 5HT1A receptor in rat brain hippocampus				Bioorg Med Chem 15: 2907-19 (2007) Article DOI: 10.1016/j.bmc.2007.02.018 BindingDB Entry DOI: 10.7270/Q20G3JTZ
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50206350 (CHEMBL390037 | N-((S)-1-{4-[4-(3-chlorophenyl)pipe...) Show SMILES Clc1cccc(c1)N1CCN(CCCCN2C(=O)C[C@H](NC(=O)CC3CC4CCC3C4)C2=O)CC1 |w:24.24,29.29,26.27,TEB:23:24:27.28:30| Show InChI InChI=1S/C27H37ClN4O3/c28-22-4-3-5-23(17-22)31-12-10-30(11-13-31)8-1-2-9-32-26(34)18-24(27(32)35)29-25(33)16-21-15-19-6-7-20(21)14-19/h3-5,17,19-21,24H,1-2,6-16,18H2,(H,29,33)/t19?,20?,21?,24-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	776	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Université Montpellier I et II Curated by ChEMBL					Assay Description Displacement of [3H]spiperone from dopaminergic D2 receptor in rat striatal membrane				Bioorg Med Chem 15: 2907-19 (2007) Article DOI: 10.1016/j.bmc.2007.02.018 BindingDB Entry DOI: 10.7270/Q20G3JTZ
					More data for this Ligand-Target Pair