BDBM50207100 4-(benzo[d][1,3]dioxol-5-yloxy)-2-(2-fluoro-4-(1H-imidazol-1-yl)phenoxy)-6-methylpyrimidine::CHEMBL388708

SMILES: Cc1cc(Oc2ccc3OCOc3c2)nc(Oc2ccc(cc2F)-n2ccnc2)n1

InChI Key: InChIKey=FDGPPDMWCPBMSY-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50207100   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Nitric oxide synthase, inducible (Homo sapiens (Human))	BDBM50207100 (4-(benzo[d][1,3]dioxol-5-yloxy)-2-(2-fluoro-4-(1H-...) Show SMILES Cc1cc(Oc2ccc3OCOc3c2)nc(Oc2ccc(cc2F)-n2ccnc2)n1 Show InChI InChI=1S/C21H15FN4O4/c1-13-8-20(29-15-3-5-18-19(10-15)28-12-27-18)25-21(24-13)30-17-4-2-14(9-16(17)22)26-7-6-23-11-26/h2-11H,12H2,1H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	92	n/a	n/a	n/a	n/a	n/a	n/a
Berlex Biosciences Curated by ChEMBL					Assay Description Inhibition of iNOS in human A172 cells after 18 to 24 hrs				Bioorg Med Chem Lett 17: 2505-8 (2007) Article DOI: 10.1016/j.bmcl.2007.02.018 BindingDB Entry DOI: 10.7270/Q2XG9QTP
					More data for this Ligand-Target Pair