BDBM50207928 1-((3-methyl-2,3-dihydrobenzofuran-2-yl)methyl)piperidine::CHEMBL375192

SMILES: CC1C(CN2CCCCC2)Oc2ccccc12

InChI Key: InChIKey=MMYNKGGNYCLPKO-UHFFFAOYSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50207928   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
P-glycoprotein 1 (Homo sapiens (Human))	BDBM50207928 (1-((3-methyl-2,3-dihydrobenzofuran-2-yl)methyl)pip...) Show SMILES CC1C(CN2CCCCC2)Oc2ccccc12 Show InChI InChI=1S/C15H21NO/c1-12-13-7-3-4-8-14(13)17-15(12)11-16-9-5-2-6-10-16/h3-4,7-8,12,15H,2,5-6,9-11H2,1H3	PDB UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	4.89E+4	n/a	n/a	n/a	n/a
University of Vienna Curated by ChEMBL					Assay Description Inhibition of P-glycoprotein expressed in MDR CCRF vcr1000 cells by daunorubicin efflux assay				J Med Chem 50: 1698-702 (2007) Article DOI: 10.1021/jm060604z BindingDB Entry DOI: 10.7270/Q2SB46JC
					More data for this Ligand-Target Pair