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BDBM50208052 1-benzyl-1-methyl-4-(2-oxo-4,4-diphenyl-imidazolidin-1-yl)-piperidinium::CHEMBL222425

SMILES: C[N+]1(Cc2ccccc2)CCC(CC1)N1CC(NC1=O)(c1ccccc1)c1ccccc1

InChI Key: InChIKey=FHBGWWMCNBBQMJ-UHFFFAOYSA-O

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50208052   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Muscarinic acetylcholine receptor M3


(Homo sapiens (Human))		BDBM50208052
PNG
(1-benzyl-1-methyl-4-(2-oxo-4,4-diphenyl-imidazolid...)
Show SMILES C[N+]1(Cc2ccccc2)CCC(CC1)N1CC(NC1=O)(c1ccccc1)c1ccccc1 |(1.29,2.89,;.49,4.2,;1.57,5.3,;3.07,4.97,;3.54,3.51,;5.04,3.17,;6.08,4.31,;5.6,5.78,;4.1,6.11,;.16,2.7,;-1.3,2.23,;-2.45,3.26,;-2.12,4.77,;-.65,5.24,;-3.91,2.78,;-4.39,1.32,;-5.93,1.32,;-6.4,2.78,;-5.16,3.69,;-5.16,5.23,;-5.22,-.04,;-6.06,-1.34,;-5.35,-2.7,;-3.81,-2.77,;-2.98,-1.46,;-3.7,-.1,;-7.48,1.32,;-8.25,2.67,;-9.79,2.67,;-10.57,1.33,;-9.79,-.02,;-8.24,-.01,)|
Show InChI InChI=1S/C28H31N3O/c1-31(21-23-11-5-2-6-12-23)19-17-26(18-20-31)30-22-28(29-27(30)32,24-13-7-3-8-14-24)25-15-9-4-10-16-25/h2-16,26H,17-22H2,1H3/p+1
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Article
PubMed
 612n/an/an/an/an/an/an/an/a



Via Zambeletti 25

Curated by ChEMBL


Assay Description
Displacement of [3H]N-methyl-scopalamine from human muscarinic M3 receptor expressed in CHOK1 cells

J Med Chem 50: 1693-7 (2007)


Article DOI: 10.1021/jm061160+
BindingDB Entry DOI: 10.7270/Q2M32VF5
More data for this
Ligand-Target Pair