Found 4 hits for monomerid = 50209875 Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Epidermal growth factor receptor
(Homo sapiens (Human)) | BDBM50209875
![PNG](/data/jpeg/tenK5020/BindingDB_50209875.png) ((2E)-4-(dimethylamino)-N-[7-ethoxy-4-({4-[(3-metho...)Show SMILES CCOc1cc2ncnc(NC3=CC(=O)C(OCc4cccc(OC)c4)=CC3=O)c2cc1NC(=O)\C=C\CN(C)C |c:26,t:11| Show InChI InChI=1S/C30H31N5O6/c1-5-40-27-15-22-21(13-24(27)33-29(38)10-7-11-35(2)3)30(32-18-31-22)34-23-14-26(37)28(16-25(23)36)41-17-19-8-6-9-20(12-19)39-4/h6-10,12-16,18H,5,11,17H2,1-4H3,(H,33,38)(H,31,32,34)/b10-7+ | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 347 | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth Research
Curated by ChEMBL
| Assay Description Inhibition of human EGFR in presence of 1 mM ATP |
Bioorg Med Chem 15: 3635-48 (2007)
Article DOI: 10.1016/j.bmc.2007.03.055 BindingDB Entry DOI: 10.7270/Q2GF0VB8 |
More data for this Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50209875
![PNG](/data/jpeg/tenK5020/BindingDB_50209875.png) ((2E)-4-(dimethylamino)-N-[7-ethoxy-4-({4-[(3-metho...)Show SMILES CCOc1cc2ncnc(NC3=CC(=O)C(OCc4cccc(OC)c4)=CC3=O)c2cc1NC(=O)\C=C\CN(C)C |c:26,t:11| Show InChI InChI=1S/C30H31N5O6/c1-5-40-27-15-22-21(13-24(27)33-29(38)10-7-11-35(2)3)30(32-18-31-22)34-23-14-26(37)28(16-25(23)36)41-17-19-8-6-9-20(12-19)39-4/h6-10,12-16,18H,5,11,17H2,1-4H3,(H,33,38)(H,31,32,34)/b10-7+ | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 372 | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth Research
Curated by ChEMBL
| Assay Description Inhibition of human VEGFR2 in presence of 1 uM ATP |
Bioorg Med Chem 15: 3635-48 (2007)
Article DOI: 10.1016/j.bmc.2007.03.055 BindingDB Entry DOI: 10.7270/Q2GF0VB8 |
More data for this Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50209875
![PNG](/data/jpeg/tenK5020/BindingDB_50209875.png) ((2E)-4-(dimethylamino)-N-[7-ethoxy-4-({4-[(3-metho...)Show SMILES CCOc1cc2ncnc(NC3=CC(=O)C(OCc4cccc(OC)c4)=CC3=O)c2cc1NC(=O)\C=C\CN(C)C |c:26,t:11| Show InChI InChI=1S/C30H31N5O6/c1-5-40-27-15-22-21(13-24(27)33-29(38)10-7-11-35(2)3)30(32-18-31-22)34-23-14-26(37)28(16-25(23)36)41-17-19-8-6-9-20(12-19)39-4/h6-10,12-16,18H,5,11,17H2,1-4H3,(H,33,38)(H,31,32,34)/b10-7+ | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 1.29E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth Research
Curated by ChEMBL
| Assay Description Inhibition of human VEGFR2 in presence of 1 mM ATP |
Bioorg Med Chem 15: 3635-48 (2007)
Article DOI: 10.1016/j.bmc.2007.03.055 BindingDB Entry DOI: 10.7270/Q2GF0VB8 |
More data for this Ligand-Target Pair | |
Epidermal growth factor receptor
(Homo sapiens (Human)) | BDBM50209875
![PNG](/data/jpeg/tenK5020/BindingDB_50209875.png) ((2E)-4-(dimethylamino)-N-[7-ethoxy-4-({4-[(3-metho...)Show SMILES CCOc1cc2ncnc(NC3=CC(=O)C(OCc4cccc(OC)c4)=CC3=O)c2cc1NC(=O)\C=C\CN(C)C |c:26,t:11| Show InChI InChI=1S/C30H31N5O6/c1-5-40-27-15-22-21(13-24(27)33-29(38)10-7-11-35(2)3)30(32-18-31-22)34-23-14-26(37)28(16-25(23)36)41-17-19-8-6-9-20(12-19)39-4/h6-10,12-16,18H,5,11,17H2,1-4H3,(H,33,38)(H,31,32,34)/b10-7+ | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 107 | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth Research
Curated by ChEMBL
| Assay Description Inhibition of human EGFR in presence of 1 uM ATP |
Bioorg Med Chem 15: 3635-48 (2007)
Article DOI: 10.1016/j.bmc.2007.03.055 BindingDB Entry DOI: 10.7270/Q2GF0VB8 |
More data for this Ligand-Target Pair | |