null

SMILES: CN(C)C\C=C\C(=O)Nc1ccc2ncnc(Nc3ccc(Br)cc3F)c2c1

InChI Key: InChIKey=SLZOGARBQLIHCR-ONEGZZNKSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50209876   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50209876 ((2E)-N-{4-[(4-bromo-2-fluorophenyl)amino]quinazoli...) Show SMILES CN(C)C\C=C\C(=O)Nc1ccc2ncnc(Nc3ccc(Br)cc3F)c2c1 Show InChI InChI=1S/C20H19BrFN5O/c1-27(2)9-3-4-19(28)25-14-6-8-17-15(11-14)20(24-12-23-17)26-18-7-5-13(21)10-16(18)22/h3-8,10-12H,9H2,1-2H3,(H,25,28)(H,23,24,26)/b4-3+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.39E+3	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibition of human VEGFR2 in presence of 1 uM ATP				Bioorg Med Chem 15: 3635-48 (2007) Article DOI: 10.1016/j.bmc.2007.03.055 BindingDB Entry DOI: 10.7270/Q2GF0VB8
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM50209876 ((2E)-N-{4-[(4-bromo-2-fluorophenyl)amino]quinazoli...) Show SMILES CN(C)C\C=C\C(=O)Nc1ccc2ncnc(Nc3ccc(Br)cc3F)c2c1 Show InChI InChI=1S/C20H19BrFN5O/c1-27(2)9-3-4-19(28)25-14-6-8-17-15(11-14)20(24-12-23-17)26-18-7-5-13(21)10-16(18)22/h3-8,10-12H,9H2,1-2H3,(H,25,28)(H,23,24,26)/b4-3+	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	704	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibition of human EGFR in presence of 1 mM ATP				Bioorg Med Chem 15: 3635-48 (2007) Article DOI: 10.1016/j.bmc.2007.03.055 BindingDB Entry DOI: 10.7270/Q2GF0VB8
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50209876 ((2E)-N-{4-[(4-bromo-2-fluorophenyl)amino]quinazoli...) Show SMILES CN(C)C\C=C\C(=O)Nc1ccc2ncnc(Nc3ccc(Br)cc3F)c2c1 Show InChI InChI=1S/C20H19BrFN5O/c1-27(2)9-3-4-19(28)25-14-6-8-17-15(11-14)20(24-12-23-17)26-18-7-5-13(21)10-16(18)22/h3-8,10-12H,9H2,1-2H3,(H,25,28)(H,23,24,26)/b4-3+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibition of human VEGFR2 in presence of 1 mM ATP				Bioorg Med Chem 15: 3635-48 (2007) Article DOI: 10.1016/j.bmc.2007.03.055 BindingDB Entry DOI: 10.7270/Q2GF0VB8
					More data for this Ligand-Target Pair