Found 4 hits for monomerid = 50209884 Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kcal/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50209884
((2E)-4-(dimethylamino)-N-(4-{[3,6-dioxo-4-(2-thien...)Show SMILES CCOc1cc2ncnc(NC3=CC(=O)C(OCc4cccs4)=CC3=O)c2cc1NC(=O)\C=C\CN(C)C |c:23,t:11| Show InChI InChI=1S/C27H27N5O5S/c1-4-36-24-13-19-18(11-21(24)30-26(35)8-5-9-32(2)3)27(29-16-28-19)31-20-12-23(34)25(14-22(20)33)37-15-17-7-6-10-38-17/h5-8,10-14,16H,4,9,15H2,1-3H3,(H,30,35)(H,28,29,31)/b8-5+ | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 76.2 | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth Research
Curated by ChEMBL
| Assay Description
Inhibition of human VEGFR2 in presence of 1 uM ATP |
Bioorg Med Chem 15: 3635-48 (2007)
Article DOI: 10.1016/j.bmc.2007.03.055
BindingDB Entry DOI: 10.7270/Q2GF0VB8 |
More data for this
Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50209884
((2E)-4-(dimethylamino)-N-(4-{[3,6-dioxo-4-(2-thien...)Show SMILES CCOc1cc2ncnc(NC3=CC(=O)C(OCc4cccs4)=CC3=O)c2cc1NC(=O)\C=C\CN(C)C |c:23,t:11| Show InChI InChI=1S/C27H27N5O5S/c1-4-36-24-13-19-18(11-21(24)30-26(35)8-5-9-32(2)3)27(29-16-28-19)31-20-12-23(34)25(14-22(20)33)37-15-17-7-6-10-38-17/h5-8,10-14,16H,4,9,15H2,1-3H3,(H,30,35)(H,28,29,31)/b8-5+ | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 298 | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth Research
Curated by ChEMBL
| Assay Description
Inhibition of human VEGFR2 in presence of 1 mM ATP |
Bioorg Med Chem 15: 3635-48 (2007)
Article DOI: 10.1016/j.bmc.2007.03.055
BindingDB Entry DOI: 10.7270/Q2GF0VB8 |
More data for this
Ligand-Target Pair | |
Epidermal growth factor receptor
(Homo sapiens (Human)) | BDBM50209884
((2E)-4-(dimethylamino)-N-(4-{[3,6-dioxo-4-(2-thien...)Show SMILES CCOc1cc2ncnc(NC3=CC(=O)C(OCc4cccs4)=CC3=O)c2cc1NC(=O)\C=C\CN(C)C |c:23,t:11| Show InChI InChI=1S/C27H27N5O5S/c1-4-36-24-13-19-18(11-21(24)30-26(35)8-5-9-32(2)3)27(29-16-28-19)31-20-12-23(34)25(14-22(20)33)37-15-17-7-6-10-38-17/h5-8,10-14,16H,4,9,15H2,1-3H3,(H,30,35)(H,28,29,31)/b8-5+ | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 47.5 | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth Research
Curated by ChEMBL
| Assay Description
Inhibition of human EGFR in presence of 1 uM ATP |
Bioorg Med Chem 15: 3635-48 (2007)
Article DOI: 10.1016/j.bmc.2007.03.055
BindingDB Entry DOI: 10.7270/Q2GF0VB8 |
More data for this
Ligand-Target Pair | |
Epidermal growth factor receptor
(Homo sapiens (Human)) | BDBM50209884
((2E)-4-(dimethylamino)-N-(4-{[3,6-dioxo-4-(2-thien...)Show SMILES CCOc1cc2ncnc(NC3=CC(=O)C(OCc4cccs4)=CC3=O)c2cc1NC(=O)\C=C\CN(C)C |c:23,t:11| Show InChI InChI=1S/C27H27N5O5S/c1-4-36-24-13-19-18(11-21(24)30-26(35)8-5-9-32(2)3)27(29-16-28-19)31-20-12-23(34)25(14-22(20)33)37-15-17-7-6-10-38-17/h5-8,10-14,16H,4,9,15H2,1-3H3,(H,30,35)(H,28,29,31)/b8-5+ | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 295 | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth Research
Curated by ChEMBL
| Assay Description
Inhibition of human EGFR in presence of 1 mM ATP |
Bioorg Med Chem 15: 3635-48 (2007)
Article DOI: 10.1016/j.bmc.2007.03.055
BindingDB Entry DOI: 10.7270/Q2GF0VB8 |
More data for this
Ligand-Target Pair | |
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