Found 4 hits for monomerid = 50209885 Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kcal/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50209885
((2E)-4-(dimethylamino)-N-(4-{[3,6-dioxo-4-(pyridin...)Show SMILES CCOc1cc2ncnc(NC3=CC(=O)C(OCc4ccccn4)=CC3=O)c2cc1NC(=O)\C=C\CN(C)C |c:24,t:11| Show InChI InChI=1S/C28H28N6O5/c1-4-38-25-14-20-19(12-22(25)32-27(37)9-7-11-34(2)3)28(31-17-30-20)33-21-13-24(36)26(15-23(21)35)39-16-18-8-5-6-10-29-18/h5-10,12-15,17H,4,11,16H2,1-3H3,(H,32,37)(H,30,31,33)/b9-7+ | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 135 | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth Research
Curated by ChEMBL
| Assay Description
Inhibition of human VEGFR2 in presence of 1 uM ATP |
Bioorg Med Chem 15: 3635-48 (2007)
Article DOI: 10.1016/j.bmc.2007.03.055
BindingDB Entry DOI: 10.7270/Q2GF0VB8 |
More data for this
Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50209885
((2E)-4-(dimethylamino)-N-(4-{[3,6-dioxo-4-(pyridin...)Show SMILES CCOc1cc2ncnc(NC3=CC(=O)C(OCc4ccccn4)=CC3=O)c2cc1NC(=O)\C=C\CN(C)C |c:24,t:11| Show InChI InChI=1S/C28H28N6O5/c1-4-38-25-14-20-19(12-22(25)32-27(37)9-7-11-34(2)3)28(31-17-30-20)33-21-13-24(36)26(15-23(21)35)39-16-18-8-5-6-10-29-18/h5-10,12-15,17H,4,11,16H2,1-3H3,(H,32,37)(H,30,31,33)/b9-7+ | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 1.01E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth Research
Curated by ChEMBL
| Assay Description
Inhibition of human VEGFR2 in presence of 1 mM ATP |
Bioorg Med Chem 15: 3635-48 (2007)
Article DOI: 10.1016/j.bmc.2007.03.055
BindingDB Entry DOI: 10.7270/Q2GF0VB8 |
More data for this
Ligand-Target Pair | |
Epidermal growth factor receptor
(Homo sapiens (Human)) | BDBM50209885
((2E)-4-(dimethylamino)-N-(4-{[3,6-dioxo-4-(pyridin...)Show SMILES CCOc1cc2ncnc(NC3=CC(=O)C(OCc4ccccn4)=CC3=O)c2cc1NC(=O)\C=C\CN(C)C |c:24,t:11| Show InChI InChI=1S/C28H28N6O5/c1-4-38-25-14-20-19(12-22(25)32-27(37)9-7-11-34(2)3)28(31-17-30-20)33-21-13-24(36)26(15-23(21)35)39-16-18-8-5-6-10-29-18/h5-10,12-15,17H,4,11,16H2,1-3H3,(H,32,37)(H,30,31,33)/b9-7+ | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 90.8 | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth Research
Curated by ChEMBL
| Assay Description
Inhibition of human EGFR in presence of 1 uM ATP |
Bioorg Med Chem 15: 3635-48 (2007)
Article DOI: 10.1016/j.bmc.2007.03.055
BindingDB Entry DOI: 10.7270/Q2GF0VB8 |
More data for this
Ligand-Target Pair | |
Epidermal growth factor receptor
(Homo sapiens (Human)) | BDBM50209885
((2E)-4-(dimethylamino)-N-(4-{[3,6-dioxo-4-(pyridin...)Show SMILES CCOc1cc2ncnc(NC3=CC(=O)C(OCc4ccccn4)=CC3=O)c2cc1NC(=O)\C=C\CN(C)C |c:24,t:11| Show InChI InChI=1S/C28H28N6O5/c1-4-38-25-14-20-19(12-22(25)32-27(37)9-7-11-34(2)3)28(31-17-30-20)33-21-13-24(36)26(15-23(21)35)39-16-18-8-5-6-10-29-18/h5-10,12-15,17H,4,11,16H2,1-3H3,(H,32,37)(H,30,31,33)/b9-7+ | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 792 | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth Research
Curated by ChEMBL
| Assay Description
Inhibition of human EGFR in presence of 1 mM ATP |
Bioorg Med Chem 15: 3635-48 (2007)
Article DOI: 10.1016/j.bmc.2007.03.055
BindingDB Entry DOI: 10.7270/Q2GF0VB8 |
More data for this
Ligand-Target Pair | |
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