BDBM50209893 7-({[1-(2,5-dimethoxy-benzenesulfonyl)-piperidin-4-yl]-methanesulfonyl-amino}-methyl)-naphthalene-2-carboxamidine::CHEMBL244219
SMILES: COc1ccc(OC)c(c1)S(=O)(=O)N1CCC(CC1)N(Cc1ccc2ccc(cc2c1)C(N)=N)S(C)(=O)=O
InChI Key: InChIKey=NUJNUGQNJZROPN-UHFFFAOYSA-N
Data: 2 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Prothrombin (Homo sapiens (Human)) | BDBM50209893![]() (7-({[1-(2,5-dimethoxy-benzenesulfonyl)-piperidin-4...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Astellas Pharma Inc. Curated by ChEMBL | Assay Description Inhibition of human thrombin | Bioorg Med Chem 15: 4175-92 (2007) Article DOI: 10.1016/j.bmc.2007.03.066 BindingDB Entry DOI: 10.7270/Q27H1J90 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Coagulation factor X (Homo sapiens (Human)) | BDBM50209893![]() (7-({[1-(2,5-dimethoxy-benzenesulfonyl)-piperidin-4...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 11 | n/a | n/a | n/a | n/a | n/a | n/a |
Astellas Pharma Inc. Curated by ChEMBL | Assay Description Inhibition of human factor 10a | Bioorg Med Chem 15: 4175-92 (2007) Article DOI: 10.1016/j.bmc.2007.03.066 BindingDB Entry DOI: 10.7270/Q27H1J90 | |||||||||||
More data for this Ligand-Target Pair |