BDBM50210216 4-(2-(aminomethyl)phenyl)-1-(bis(3-fluorophenyl)methyl)piperidin-4-ol::CHEMBL400036

SMILES: NCc1ccccc1C1(O)CCN(CC1)C(c1cccc(F)c1)c1cccc(F)c1

InChI Key: InChIKey=OVMRKPFMLHSDOF-UHFFFAOYSA-N

Data: 4 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50210216   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Nociceptin receptor (Homo sapiens (Human))	BDBM50210216 (4-(2-(aminomethyl)phenyl)-1-(bis(3-fluorophenyl)me...) Show SMILES NCc1ccccc1C1(O)CCN(CC1)C(c1cccc(F)c1)c1cccc(F)c1 Show InChI InChI=1S/C25H26F2N2O/c26-21-8-3-6-18(15-21)24(19-7-4-9-22(27)16-19)29-13-11-25(30,12-14-29)23-10-2-1-5-20(23)17-28/h1-10,15-16,24,30H,11-14,17,28H2	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	9.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Schering-Plough Research Institute Curated by ChEMBL					Assay Description Displacement of [125I][Tyr14]nociceptin FQ from human NOP receptor expressed in CHO cell membrane				Bioorg Med Chem Lett 17: 3028-33 (2007) Article DOI: 10.1016/j.bmcl.2007.03.062 BindingDB Entry DOI: 10.7270/Q2Z31ZBS
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Homo sapiens (Human))	BDBM50210216 (4-(2-(aminomethyl)phenyl)-1-(bis(3-fluorophenyl)me...) Show SMILES NCc1ccccc1C1(O)CCN(CC1)C(c1cccc(F)c1)c1cccc(F)c1 Show InChI InChI=1S/C25H26F2N2O/c26-21-8-3-6-18(15-21)24(19-7-4-9-22(27)16-19)29-13-11-25(30,12-14-29)23-10-2-1-5-20(23)17-28/h1-10,15-16,24,30H,11-14,17,28H2	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	616	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Schering-Plough Research Institute Curated by ChEMBL					Assay Description Displacement of [3H]diprenorphine from human MOP receptor expressed in CHO cell membrane				Bioorg Med Chem Lett 17: 3028-33 (2007) Article DOI: 10.1016/j.bmcl.2007.03.062 BindingDB Entry DOI: 10.7270/Q2Z31ZBS
					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Homo sapiens (Human))	BDBM50210216 (4-(2-(aminomethyl)phenyl)-1-(bis(3-fluorophenyl)me...) Show SMILES NCc1ccccc1C1(O)CCN(CC1)C(c1cccc(F)c1)c1cccc(F)c1 Show InChI InChI=1S/C25H26F2N2O/c26-21-8-3-6-18(15-21)24(19-7-4-9-22(27)16-19)29-13-11-25(30,12-14-29)23-10-2-1-5-20(23)17-28/h1-10,15-16,24,30H,11-14,17,28H2	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	771	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Schering-Plough Research Institute Curated by ChEMBL					Assay Description Displacement of [3H]diprenorphine from human KOP receptor expressed in CHO cell membrane				Bioorg Med Chem Lett 17: 3028-33 (2007) Article DOI: 10.1016/j.bmcl.2007.03.062 BindingDB Entry DOI: 10.7270/Q2Z31ZBS
					More data for this Ligand-Target Pair
Delta-type opioid receptor (Homo sapiens (Human))	BDBM50210216 (4-(2-(aminomethyl)phenyl)-1-(bis(3-fluorophenyl)me...) Show SMILES NCc1ccccc1C1(O)CCN(CC1)C(c1cccc(F)c1)c1cccc(F)c1 Show InChI InChI=1S/C25H26F2N2O/c26-21-8-3-6-18(15-21)24(19-7-4-9-22(27)16-19)29-13-11-25(30,12-14-29)23-10-2-1-5-20(23)17-28/h1-10,15-16,24,30H,11-14,17,28H2	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	9.38E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Schering-Plough Research Institute Curated by ChEMBL					Assay Description Displacement of [3H]diprenorphine from human DOP receptor expressed in CHO cell membrane				Bioorg Med Chem Lett 17: 3028-33 (2007) Article DOI: 10.1016/j.bmcl.2007.03.062 BindingDB Entry DOI: 10.7270/Q2Z31ZBS
					More data for this Ligand-Target Pair