BDBM50210725 5-(1-(6-(5-chloro-2-methoxybenzyl)-2,5-dioxo-1,4-diazepane-4-carboxamido)propyl)-2-hydroxybenzoic acid::CHEMBL396333

SMILES: CCC(NC(=O)N1CC(=O)NCC(Cc2cc(Cl)ccc2OC)C1=O)c1ccc(O)c(c1)C(O)=O

InChI Key: InChIKey=CYUDVVQWJVHMGL-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50210725   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Chymase (Homo sapiens (Human))	BDBM50210725 (5-(1-(6-(5-chloro-2-methoxybenzyl)-2,5-dioxo-1,4-d...) Show SMILES CCC(NC(=O)N1CC(=O)NCC(Cc2cc(Cl)ccc2OC)C1=O)c1ccc(O)c(c1)C(O)=O Show InChI InChI=1S/C24H26ClN3O7/c1-3-18(13-4-6-19(29)17(10-13)23(32)33)27-24(34)28-12-21(30)26-11-15(22(28)31)8-14-9-16(25)5-7-20(14)35-2/h4-7,9-10,15,18,29H,3,8,11-12H2,1-2H3,(H,26,30)(H,27,34)(H,32,33)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	410	n/a	n/a	n/a	n/a	n/a	n/a
Daiichi Asubio Pharma Co., Ltd Curated by ChEMBL					Assay Description Inhibition of human recombinant chymase				Bioorg Med Chem Lett 17: 3435-9 (2007) Article DOI: 10.1016/j.bmcl.2007.03.085 BindingDB Entry DOI: 10.7270/Q2MK6CKH
					More data for this Ligand-Target Pair
Chymase (Homo sapiens (Human))	BDBM50210725 (5-(1-(6-(5-chloro-2-methoxybenzyl)-2,5-dioxo-1,4-d...) Show SMILES CCC(NC(=O)N1CC(=O)NCC(Cc2cc(Cl)ccc2OC)C1=O)c1ccc(O)c(c1)C(O)=O Show InChI InChI=1S/C24H26ClN3O7/c1-3-18(13-4-6-19(29)17(10-13)23(32)33)27-24(34)28-12-21(30)26-11-15(22(28)31)8-14-9-16(25)5-7-20(14)35-2/h4-7,9-10,15,18,29H,3,8,11-12H2,1-2H3,(H,26,30)(H,27,34)(H,32,33)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
Daiichi Asubio Pharma Co., Ltd Curated by ChEMBL					Assay Description Inhibition of human recombinant chymase				Bioorg Med Chem Lett 17: 3435-9 (2007) Article DOI: 10.1016/j.bmcl.2007.03.085 BindingDB Entry DOI: 10.7270/Q2MK6CKH
					More data for this Ligand-Target Pair