BDBM50210741 4-(1-(6-(5-chloro-2-methoxybenzyl)-2,5-dioxo-1,4-diazepane-4-carboxamido)propyl)benzoic acid::CHEMBL247779

SMILES: CCC(NC(=O)N1CC(=O)NCC(Cc2cc(Cl)ccc2OC)C1=O)c1ccc(cc1)C(O)=O

InChI Key: InChIKey=FRLHVSYQUWWEIJ-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50210741   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Chymase (Homo sapiens (Human))	BDBM50210741 (4-(1-(6-(5-chloro-2-methoxybenzyl)-2,5-dioxo-1,4-d...) Show SMILES CCC(NC(=O)N1CC(=O)NCC(Cc2cc(Cl)ccc2OC)C1=O)c1ccc(cc1)C(O)=O Show InChI InChI=1S/C24H26ClN3O6/c1-3-19(14-4-6-15(7-5-14)23(31)32)27-24(33)28-13-21(29)26-12-17(22(28)30)10-16-11-18(25)8-9-20(16)34-2/h4-9,11,17,19H,3,10,12-13H2,1-2H3,(H,26,29)(H,27,33)(H,31,32)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Daiichi Asubio Pharma Co., Ltd Curated by ChEMBL					Assay Description Inhibition of human recombinant chymase				Bioorg Med Chem Lett 17: 3435-9 (2007) Article DOI: 10.1016/j.bmcl.2007.03.085 BindingDB Entry DOI: 10.7270/Q2MK6CKH
					More data for this Ligand-Target Pair
Chymase (Homo sapiens (Human))	BDBM50210741 (4-(1-(6-(5-chloro-2-methoxybenzyl)-2,5-dioxo-1,4-d...) Show SMILES CCC(NC(=O)N1CC(=O)NCC(Cc2cc(Cl)ccc2OC)C1=O)c1ccc(cc1)C(O)=O Show InChI InChI=1S/C24H26ClN3O6/c1-3-19(14-4-6-15(7-5-14)23(31)32)27-24(33)28-13-21(29)26-12-17(22(28)30)10-16-11-18(25)8-9-20(16)34-2/h4-9,11,17,19H,3,10,12-13H2,1-2H3,(H,26,29)(H,27,33)(H,31,32)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	470	n/a	n/a	n/a	n/a	n/a	n/a
Daiichi Asubio Pharma Co., Ltd Curated by ChEMBL					Assay Description Inhibition of human recombinant chymase				Bioorg Med Chem Lett 17: 3435-9 (2007) Article DOI: 10.1016/j.bmcl.2007.03.085 BindingDB Entry DOI: 10.7270/Q2MK6CKH
					More data for this Ligand-Target Pair