Found 4 hits for monomerid = 50211440 Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kcal/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Cyclin-dependent kinase 2
(Homo sapiens (Human)) | BDBM50211440
(4-(5-chloro-4-(H-imidazo[1,2-a]pyridin-3-yl)pyrimi...)Show SMILES CCNC(=O)N1CCC(CC1)Nc1ncc(Cl)c(n1)-c1cnc2ccccn12 Show InChI InChI=1S/C19H22ClN7O/c1-2-21-19(28)26-9-6-13(7-10-26)24-18-23-11-14(20)17(25-18)15-12-22-16-5-3-4-8-27(15)16/h3-5,8,11-13H,2,6-7,9-10H2,1H3,(H,21,28)(H,23,24,25) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 605 | n/a | n/a | n/a | n/a | n/a | n/a |
UCB
Curated by ChEMBL
| Assay Description
Inhibition of CDK2 by IMAP technology |
Bioorg Med Chem Lett 17: 3463-7 (2007)
Article DOI: 10.1016/j.bmcl.2007.03.078
BindingDB Entry DOI: 10.7270/Q2959H7W |
More data for this
Ligand-Target Pair | |
Mitogen-activated protein kinase 9
(Homo sapiens (Human)) | BDBM50211440
(4-(5-chloro-4-(H-imidazo[1,2-a]pyridin-3-yl)pyrimi...)Show SMILES CCNC(=O)N1CCC(CC1)Nc1ncc(Cl)c(n1)-c1cnc2ccccn12 Show InChI InChI=1S/C19H22ClN7O/c1-2-21-19(28)26-9-6-13(7-10-26)24-18-23-11-14(20)17(25-18)15-12-22-16-5-3-4-8-27(15)16/h3-5,8,11-13H,2,6-7,9-10H2,1H3,(H,21,28)(H,23,24,25) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 55 | n/a | n/a | n/a | n/a | n/a | n/a |
UCB
Curated by ChEMBL
| Assay Description
Inhibition of JNK2 |
Bioorg Med Chem Lett 17: 3463-7 (2007)
Article DOI: 10.1016/j.bmcl.2007.03.078
BindingDB Entry DOI: 10.7270/Q2959H7W |
More data for this
Ligand-Target Pair | |
Transcription factor Jun
(Homo sapiens (Human)) | BDBM50211440
(4-(5-chloro-4-(H-imidazo[1,2-a]pyridin-3-yl)pyrimi...)Show SMILES CCNC(=O)N1CCC(CC1)Nc1ncc(Cl)c(n1)-c1cnc2ccccn12 Show InChI InChI=1S/C19H22ClN7O/c1-2-21-19(28)26-9-6-13(7-10-26)24-18-23-11-14(20)17(25-18)15-12-22-16-5-3-4-8-27(15)16/h3-5,8,11-13H,2,6-7,9-10H2,1H3,(H,21,28)(H,23,24,25) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 7.72E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
UCB
Curated by ChEMBL
| Assay Description
Inhibition of cJun translocation in IL1beta-stimulated A549 cells |
Bioorg Med Chem Lett 17: 3463-7 (2007)
Article DOI: 10.1016/j.bmcl.2007.03.078
BindingDB Entry DOI: 10.7270/Q2959H7W |
More data for this
Ligand-Target Pair | |
Mitogen-activated protein kinase 8
(Homo sapiens (Human)) | BDBM50211440
(4-(5-chloro-4-(H-imidazo[1,2-a]pyridin-3-yl)pyrimi...)Show SMILES CCNC(=O)N1CCC(CC1)Nc1ncc(Cl)c(n1)-c1cnc2ccccn12 Show InChI InChI=1S/C19H22ClN7O/c1-2-21-19(28)26-9-6-13(7-10-26)24-18-23-11-14(20)17(25-18)15-12-22-16-5-3-4-8-27(15)16/h3-5,8,11-13H,2,6-7,9-10H2,1H3,(H,21,28)(H,23,24,25) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 41 | n/a | n/a | n/a | n/a | n/a | n/a |
UCB
Curated by ChEMBL
| Assay Description
Inhibition of JNK1 |
Bioorg Med Chem Lett 17: 3463-7 (2007)
Article DOI: 10.1016/j.bmcl.2007.03.078
BindingDB Entry DOI: 10.7270/Q2959H7W |
More data for this
Ligand-Target Pair | |
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