BDBM50211684 4'-(2-furyl)-N-(2-methoxypyrimidin-5-yl)-4,5'-bipyrimidin-2'-amine::CHEMBL226236

SMILES: COc1ncc(Nc2ncc(-c3ccncn3)c(n2)-c2ccco2)cn1

InChI Key: InChIKey=ONXHHAADYYTDKN-UHFFFAOYSA-N

Data: 4 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50211684   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Adenosine receptor A2b (Homo sapiens (Human))	BDBM50211684 (4'-(2-furyl)-N-(2-methoxypyrimidin-5-yl)-4,5'-bipy...) Show SMILES COc1ncc(Nc2ncc(-c3ccncn3)c(n2)-c2ccco2)cn1 Show InChI InChI=1S/C17H13N7O2/c1-25-17-20-7-11(8-21-17)23-16-19-9-12(13-4-5-18-10-22-13)15(24-16)14-3-2-6-26-14/h2-10H,1H3,(H,19,23,24)	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	39	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Almirall Curated by ChEMBL					Assay Description Displacement of [3H]DPCPX from human A2B receptor expressed in HEK293 cells				J Med Chem 50: 2732-6 (2007) Checked by Author Article DOI: 10.1021/jm061333v BindingDB Entry DOI: 10.7270/Q2862G32
					More data for this Ligand-Target Pair
Adenosine receptor A3 (Homo sapiens (Human))	BDBM50211684 (4'-(2-furyl)-N-(2-methoxypyrimidin-5-yl)-4,5'-bipy...) Show SMILES COc1ncc(Nc2ncc(-c3ccncn3)c(n2)-c2ccco2)cn1 Show InChI InChI=1S/C17H13N7O2/c1-25-17-20-7-11(8-21-17)23-16-19-9-12(13-4-5-18-10-22-13)15(24-16)14-3-2-6-26-14/h2-10H,1H3,(H,19,23,24)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Almirall Curated by ChEMBL					Assay Description Displacement of [2H]NECA from human A3 receptor expressed in HeLa cells				J Med Chem 50: 2732-6 (2007) Checked by Author Article DOI: 10.1021/jm061333v BindingDB Entry DOI: 10.7270/Q2862G32
					More data for this Ligand-Target Pair
Adenosine receptor A2a (Homo sapiens (Human))	BDBM50211684 (4'-(2-furyl)-N-(2-methoxypyrimidin-5-yl)-4,5'-bipy...) Show SMILES COc1ncc(Nc2ncc(-c3ccncn3)c(n2)-c2ccco2)cn1 Show InChI InChI=1S/C17H13N7O2/c1-25-17-20-7-11(8-21-17)23-16-19-9-12(13-4-5-18-10-22-13)15(24-16)14-3-2-6-26-14/h2-10H,1H3,(H,19,23,24)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>2.50E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Almirall Curated by ChEMBL					Assay Description Displacement of [3H]ZM241385 from human A2A receptor expressed in HeLa cells				J Med Chem 50: 2732-6 (2007) Checked by Author Article DOI: 10.1021/jm061333v BindingDB Entry DOI: 10.7270/Q2862G32
					More data for this Ligand-Target Pair
Adenosine receptor A1 (Homo sapiens (Human))	BDBM50211684 (4'-(2-furyl)-N-(2-methoxypyrimidin-5-yl)-4,5'-bipy...) Show SMILES COc1ncc(Nc2ncc(-c3ccncn3)c(n2)-c2ccco2)cn1 Show InChI InChI=1S/C17H13N7O2/c1-25-17-20-7-11(8-21-17)23-16-19-9-12(13-4-5-18-10-22-13)15(24-16)14-3-2-6-26-14/h2-10H,1H3,(H,19,23,24)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Almirall Curated by ChEMBL					Assay Description Displacement of [3H]DPCPX from human A1 receptor expressed in CHO cells				J Med Chem 50: 2732-6 (2007) Checked by Author Article DOI: 10.1021/jm061333v BindingDB Entry DOI: 10.7270/Q2862G32
					More data for this Ligand-Target Pair