BDBM50211768 CHEMBL226277::{3-[(1R,2S,7R,8S,9R)-3,3,7-trimethyltricyclo[5.4.0.02,9]undec-8-yl]propyl}phosphonic acid
SMILES: C[C@]12CCCC(C)(C)[C@H]3[C@H](CC[C@@H]13)[C@@H]2CCCP(O)(O)=O
InChI Key: InChIKey=VPPAXHIJGOHXRA-LBKYZSNHSA-N
Data: 1 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Uridine-5'-diphosphoglucuronosyltransferase 2B7 (Homo sapiens (Human)) | BDBM50211768 (CHEMBL226277 | {3-[(1R,2S,7R,8S,9R)-3,3,7-trimethy...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 3.20E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Helsinki Curated by ChEMBL | Assay Description Inhibition of human UGT2B7 assessed as reduction of estriol glucuronidation | J Med Chem 50: 2655-64 (2007) Article DOI: 10.1021/jm061204e BindingDB Entry DOI: 10.7270/Q23F4QF2 | |||||||||||
More data for this Ligand-Target Pair |