BDBM50211772 CHEMBL375253::diethyl {(2R)-2-hydroxy-2-[(1R,2S,7S,8S,9S)-3,3,7-trimethyltricyclo[5.4.0.02,9]undec-8-yl]ethyl}phosphonate
SMILES: CCOP(=O)(C[C@H](O)[C@H]1[C@H]2CC[C@@H]3[C@@H]2C(C)(C)CCC[C@]13C)OCC
InChI Key: InChIKey=HKYADLMJLPBMTK-ZJNNMKFESA-N
Data: 1 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Uridine-5'-diphosphoglucuronosyltransferase 2B7 (Homo sapiens (Human)) | BDBM50211772 (CHEMBL375253 | diethyl {(2R)-2-hydroxy-2-[(1R,2S,7...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Helsinki Curated by ChEMBL | Assay Description Inhibition of human UGT2B7 assessed as reduction of estriol glucuronidation | J Med Chem 50: 2655-64 (2007) Article DOI: 10.1021/jm061204e BindingDB Entry DOI: 10.7270/Q23F4QF2 | |||||||||||
More data for this Ligand-Target Pair |