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SMILES: N#Cc1cnc(Nc2ccc3ccccc3c2)nc1-c1ccccc1

InChI Key: InChIKey=XOZOUVPLBSWHOC-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50212015   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50212015 (2-(naphthalen-2-ylamino)-4-phenylpyrimidine-5-carb...) Show SMILES N#Cc1cnc(Nc2ccc3ccccc3c2)nc1-c1ccccc1 Show InChI InChI=1S/C21H14N4/c22-13-18-14-23-21(25-20(18)16-7-2-1-3-8-16)24-19-11-10-15-6-4-5-9-17(15)12-19/h1-12,14H,(H,23,24,25)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Inhibition of VEGFR2 activity				Bioorg Med Chem Lett 17: 3266-70 (2007) Article DOI: 10.1016/j.bmcl.2007.04.021 BindingDB Entry DOI: 10.7270/Q2GQ6XFG
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 1 (Homo sapiens (Human))	BDBM50212015 (2-(naphthalen-2-ylamino)-4-phenylpyrimidine-5-carb...) Show SMILES N#Cc1cnc(Nc2ccc3ccccc3c2)nc1-c1ccccc1 Show InChI InChI=1S/C21H14N4/c22-13-18-14-23-21(25-20(18)16-7-2-1-3-8-16)24-19-11-10-15-6-4-5-9-17(15)12-19/h1-12,14H,(H,23,24,25)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Inhibition of CDK1 activity				Bioorg Med Chem Lett 17: 3266-70 (2007) Article DOI: 10.1016/j.bmcl.2007.04.021 BindingDB Entry DOI: 10.7270/Q2GQ6XFG
					More data for this Ligand-Target Pair