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SMILES: CC(C)N(C)C(=O)C1CCC(=CC1)c1nnn(c1C)-c1cccnc1F

InChI Key: InChIKey=UGYUKHCPVLGRRG-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50212328   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Metabotropic glutamate receptor 1


(Homo sapiens (Human))		BDBM50212328
PNG
(4-(1-(2-fluoropyridin-3-yl)-5-methyl-1H-1,2,3-tria...)
Show SMILES CC(C)N(C)C(=O)C1CCC(=CC1)c1nnn(c1C)-c1cccnc1F |w:7.6,c:10|
Show InChI InChI=1S/C19H24FN5O/c1-12(2)24(4)19(26)15-9-7-14(8-10-15)17-13(3)25(23-22-17)16-6-5-11-21-18(16)20/h5-7,11-12,15H,8-10H2,1-4H3
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 6n/an/an/an/an/an/a



Lilly Research Labs

Curated by ChEMBL


Assay Description
Antagonist activity at mGlu1 receptor

J Med Chem 50: 2563-8 (2007)


Article DOI: 10.1021/jm060950g
BindingDB Entry DOI: 10.7270/Q2XS5W7Q
More data for this
Ligand-Target Pair