BDBM50212521 3-(4'-hydroxy-biphenyl-4-yl)-1,4-dihydro-indeno[1,2-c]pyrazole-5-carboxylic acid benzylamide::CHEMBL393195

SMILES: Oc1ccc(cc1)-c1ccc(cc1)-c1n[nH]c-2c1Cc1c-2cccc1C(=O)NCc1ccccc1

InChI Key: InChIKey=XMWAVSCSFFSYTR-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50212521   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase Chk1 (Homo sapiens (Human))	BDBM50212521 (3-(4'-hydroxy-biphenyl-4-yl)-1,4-dihydro-indeno[1,...) Show SMILES Oc1ccc(cc1)-c1ccc(cc1)-c1n[nH]c-2c1Cc1c-2cccc1C(=O)NCc1ccccc1 Show InChI InChI=1S/C30H23N3O2/c34-23-15-13-21(14-16-23)20-9-11-22(12-10-20)28-27-17-26-24(29(27)33-32-28)7-4-8-25(26)30(35)31-18-19-5-2-1-3-6-19/h1-16,34H,17-18H2,(H,31,35)(H,32,33)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibition of recombinant CHK-mediated Cdc25C phosphorylation after 30 mins				Bioorg Med Chem Lett 17: 3618-23 (2007) Article DOI: 10.1016/j.bmcl.2007.04.055 BindingDB Entry DOI: 10.7270/Q2DR2V6Q
					More data for this Ligand-Target Pair