BDBM50213130 (S)-N-(8-(hydroxyamino)-1,8-dioxo-1-(quinolin-8-ylamino)octan-2-yl)picolinamide::CHEMBL391569

SMILES: ONC(=O)CCCCC[C@H](NC(=O)c1ccccn1)C(=O)Nc1cccc2cccnc12

InChI Key: InChIKey=KRTCYVKYLLHIIK-IBGZPJMESA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50213130   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histone deacetylase 1 (Homo sapiens (Human))	BDBM50213130 ((S)-N-(8-(hydroxyamino)-1,8-dioxo-1-(quinolin-8-yl...) Show SMILES ONC(=O)CCCCC[C@H](NC(=O)c1ccccn1)C(=O)Nc1cccc2cccnc12 Show InChI InChI=1S/C23H25N5O4/c29-20(28-32)13-3-1-2-11-19(27-22(30)18-10-4-5-14-24-18)23(31)26-17-12-6-8-16-9-7-15-25-21(16)17/h4-10,12,14-15,19,32H,1-3,11,13H2,(H,26,31)(H,27,30)(H,28,29)/t19-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of human HDAC 1				Bioorg Med Chem Lett 17: 3969-71 (2007) Article DOI: 10.1016/j.bmcl.2007.04.089 BindingDB Entry DOI: 10.7270/Q2M908CJ
					More data for this Ligand-Target Pair