Found 2 hits for monomerid = 50213274 Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Protein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha
(Rattus norvegicus-Rattus norvegicus (rat)) | BDBM50213274
(CHEMBL3350314)Show SMILES CSCC[C@H](NC(=O)[C@@H]1Cc2ccccc2CN1C(=O)[C@H](NC(=O)[C@H](CS)NC(=O)[C@@H](N)CCCCN)C(C)C)C(O)=O Show InChI InChI=1S/C29H46N6O6S2/c1-17(2)24(34-26(37)22(16-42)33-25(36)20(31)10-6-7-12-30)28(39)35-15-19-9-5-4-8-18(19)14-23(35)27(38)32-21(29(40)41)11-13-43-3/h4-5,8-9,17,20-24,42H,6-7,10-16,30-31H2,1-3H3,(H,32,38)(H,33,36)(H,34,37)(H,40,41)/t20-,21-,22-,23-,24+/m0/s1 | PDB
KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL KEGG PC cid PC sid UniChem
Similars
| Article
| n/a | n/a | 1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description Inhibition of farnesyl transferase (FTase) of rat brain |
Bioorg Med Chem Lett 5: 1779-1784 (1995)
Article DOI: 10.1016/0960-894X(95)00314-J BindingDB Entry DOI: 10.7270/Q2H41RDH |
More data for this Ligand-Target Pair | |
Protein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha
(Rattus norvegicus-Rattus norvegicus (rat)) | BDBM50213274
(CHEMBL3350314)Show SMILES CSCC[C@H](NC(=O)[C@@H]1Cc2ccccc2CN1C(=O)[C@H](NC(=O)[C@H](CS)NC(=O)[C@@H](N)CCCCN)C(C)C)C(O)=O Show InChI InChI=1S/C29H46N6O6S2/c1-17(2)24(34-26(37)22(16-42)33-25(36)20(31)10-6-7-12-30)28(39)35-15-19-9-5-4-8-18(19)14-23(35)27(38)32-21(29(40)41)11-13-43-3/h4-5,8-9,17,20-24,42H,6-7,10-16,30-31H2,1-3H3,(H,32,38)(H,33,36)(H,34,37)(H,40,41)/t20-,21-,22-,23-,24+/m0/s1 | PDB
KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL KEGG PC cid PC sid UniChem
Similars
| Article
| n/a | n/a | 5.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description Inhibition of farnesyl transferase (FTase) of rat brain |
Bioorg Med Chem Lett 5: 1779-1784 (1995)
Article DOI: 10.1016/0960-894X(95)00314-J BindingDB Entry DOI: 10.7270/Q2H41RDH |
More data for this Ligand-Target Pair | |