null

SMILES: Cc1nc(sc1CSc1ccc2n(CC(O)=O)ccc2c1)C(F)(F)F

InChI Key: InChIKey=SBRYXHXGTIWXKI-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50213331   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Peroxisome proliferator-activated receptor gamma (Homo sapiens (Human))	BDBM50213331 (2-(5-((4-methyl-2-(trifluoromethyl)thiazol-5-yl)me...) Show SMILES Cc1nc(sc1CSc1ccc2n(CC(O)=O)ccc2c1)C(F)(F)F Show InChI InChI=1S/C16H13F3N2O2S2/c1-9-13(25-15(20-9)16(17,18)19)8-24-11-2-3-12-10(6-11)4-5-21(12)7-14(22)23/h2-6H,7-8H2,1H3,(H,22,23)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Displacement of [3H]5-(4-(3-(5-methyl-2-phenyloxazol-4-yl)propanoyl)benzyl)thiazolidine-2,4-dione from human PPARgamma after 2 hrs by SPA				Bioorg Med Chem Lett 17: 3630-5 (2007) Article DOI: 10.1016/j.bmcl.2007.04.047 BindingDB Entry DOI: 10.7270/Q2ZK5GBB
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor delta (Homo sapiens (Human))	BDBM50213331 (2-(5-((4-methyl-2-(trifluoromethyl)thiazol-5-yl)me...) Show SMILES Cc1nc(sc1CSc1ccc2n(CC(O)=O)ccc2c1)C(F)(F)F Show InChI InChI=1S/C16H13F3N2O2S2/c1-9-13(25-15(20-9)16(17,18)19)8-24-11-2-3-12-10(6-11)4-5-21(12)7-14(22)23/h2-6H,7-8H2,1H3,(H,22,23)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	4	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Agonist activity at human PPARdelta in HepG2 cells by GAL4-luciferase reporter gene assay				Bioorg Med Chem Lett 17: 3630-5 (2007) Article DOI: 10.1016/j.bmcl.2007.04.047 BindingDB Entry DOI: 10.7270/Q2ZK5GBB
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor alpha (Homo sapiens (Human))	BDBM50213331 (2-(5-((4-methyl-2-(trifluoromethyl)thiazol-5-yl)me...) Show SMILES Cc1nc(sc1CSc1ccc2n(CC(O)=O)ccc2c1)C(F)(F)F Show InChI InChI=1S/C16H13F3N2O2S2/c1-9-13(25-15(20-9)16(17,18)19)8-24-11-2-3-12-10(6-11)4-5-21(12)7-14(22)23/h2-6H,7-8H2,1H3,(H,22,23)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	172	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Displacement of [3H]2-(4-(2-(3-(2,4-difluorophenyl)-1-heptylureido)ethyl)phenoxy)-2-methylbutanoic acid from human PPARalpha after 30 mins by SPA				Bioorg Med Chem Lett 17: 3630-5 (2007) Article DOI: 10.1016/j.bmcl.2007.04.047 BindingDB Entry DOI: 10.7270/Q2ZK5GBB
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor delta (Homo sapiens (Human))	BDBM50213331 (2-(5-((4-methyl-2-(trifluoromethyl)thiazol-5-yl)me...) Show SMILES Cc1nc(sc1CSc1ccc2n(CC(O)=O)ccc2c1)C(F)(F)F Show InChI InChI=1S/C16H13F3N2O2S2/c1-9-13(25-15(20-9)16(17,18)19)8-24-11-2-3-12-10(6-11)4-5-21(12)7-14(22)23/h2-6H,7-8H2,1H3,(H,22,23)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.80	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Displacement of [3H]2-(4-(3-(4-acetyl-3-hydroxy-2 propyl-phenoxy)propoxy)phenoxy)acetic acid from human PPARdelta after 30 mins by SPA				Bioorg Med Chem Lett 17: 3630-5 (2007) Article DOI: 10.1016/j.bmcl.2007.04.047 BindingDB Entry DOI: 10.7270/Q2ZK5GBB
					More data for this Ligand-Target Pair