Found 4 hits for monomerid = 50213945 Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Matrix metalloproteinase-14 (MMP14)
(Homo sapiens (Human)) | BDBM50213945
(3-((4-(but-2-ynyloxy)phenylsulfonyl)methyl)-N-hydr...)Show SMILES CC#CCOc1ccc(cc1)S(=O)(=O)CC1(CCCN(C1)S(=O)(=O)C(C)C)C(=O)NO |w:15.15| Show InChI InChI=1S/C20H28N2O7S2/c1-4-5-13-29-17-7-9-18(10-8-17)30(25,26)15-20(19(23)21-24)11-6-12-22(14-20)31(27,28)16(2)3/h7-10,16,24H,6,11-15H2,1-3H3,(H,21,23) | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 5.64E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth Research
Curated by ChEMBL
| Assay Description Inhibition of MMP14 |
Bioorg Med Chem Lett 17: 4333-7 (2007)
Article DOI: 10.1016/j.bmcl.2007.05.022 BindingDB Entry DOI: 10.7270/Q2CN73K3 |
More data for this Ligand-Target Pair | |
72 kDa type IV collagenase
(Homo sapiens (Human)) | BDBM50213945
(3-((4-(but-2-ynyloxy)phenylsulfonyl)methyl)-N-hydr...)Show SMILES CC#CCOc1ccc(cc1)S(=O)(=O)CC1(CCCN(C1)S(=O)(=O)C(C)C)C(=O)NO |w:15.15| Show InChI InChI=1S/C20H28N2O7S2/c1-4-5-13-29-17-7-9-18(10-8-17)30(25,26)15-20(19(23)21-24)11-6-12-22(14-20)31(27,28)16(2)3/h7-10,16,24H,6,11-15H2,1-3H3,(H,21,23) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt UniProtKB/TrEMBL
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 700 | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth Research
Curated by ChEMBL
| Assay Description Inhibition of MMP2 |
Bioorg Med Chem Lett 17: 4333-7 (2007)
Article DOI: 10.1016/j.bmcl.2007.05.022 BindingDB Entry DOI: 10.7270/Q2CN73K3 |
More data for this Ligand-Target Pair | |
Disintegrin and metalloproteinase domain-containing protein 17
(Homo sapiens (Human)) | BDBM50213945
(3-((4-(but-2-ynyloxy)phenylsulfonyl)methyl)-N-hydr...)Show SMILES CC#CCOc1ccc(cc1)S(=O)(=O)CC1(CCCN(C1)S(=O)(=O)C(C)C)C(=O)NO |w:15.15| Show InChI InChI=1S/C20H28N2O7S2/c1-4-5-13-29-17-7-9-18(10-8-17)30(25,26)15-20(19(23)21-24)11-6-12-22(14-20)31(27,28)16(2)3/h7-10,16,24H,6,11-15H2,1-3H3,(H,21,23) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt UniProtKB/TrEMBL
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 5.40 | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth Research
Curated by ChEMBL
| Assay Description Inhibition of TACE by FRET assay |
Bioorg Med Chem Lett 17: 4333-7 (2007)
Article DOI: 10.1016/j.bmcl.2007.05.022 BindingDB Entry DOI: 10.7270/Q2CN73K3 |
More data for this Ligand-Target Pair | |
Collagenase 3
(Homo sapiens (Human)) | BDBM50213945
(3-((4-(but-2-ynyloxy)phenylsulfonyl)methyl)-N-hydr...)Show SMILES CC#CCOc1ccc(cc1)S(=O)(=O)CC1(CCCN(C1)S(=O)(=O)C(C)C)C(=O)NO |w:15.15| Show InChI InChI=1S/C20H28N2O7S2/c1-4-5-13-29-17-7-9-18(10-8-17)30(25,26)15-20(19(23)21-24)11-6-12-22(14-20)31(27,28)16(2)3/h7-10,16,24H,6,11-15H2,1-3H3,(H,21,23) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 1.19E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth Research
Curated by ChEMBL
| Assay Description Inhibition of MMP13 |
Bioorg Med Chem Lett 17: 4333-7 (2007)
Article DOI: 10.1016/j.bmcl.2007.05.022 BindingDB Entry DOI: 10.7270/Q2CN73K3 |
More data for this Ligand-Target Pair | |