BDBM50213975 4-(2-((R)-2-(4-methylocta-1,3-dienyl)-5-oxopyrrolidin-1-yl)ethyl)benzoic acid::CHEMBL251504

SMILES: CCCC\C(C)=C\C=C\[C@H]1CCC(=O)N1CCc1ccc(cc1)C(O)=O

InChI Key: InChIKey=SJKJSDLRYXXUDS-BJSAIBKMSA-N

Data: 4 KI  2 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50213975   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Prostaglandin E2 receptor EP2 subtype (Homo sapiens (Human))	BDBM50213975 (4-(2-((R)-2-(4-methylocta-1,3-dienyl)-5-oxopyrroli...) Show SMILES CCCC\C(C)=C\C=C\[C@H]1CCC(=O)N1CCc1ccc(cc1)C(O)=O Show InChI InChI=1S/C22H29NO3/c1-3-4-6-17(2)7-5-8-20-13-14-21(24)23(20)16-15-18-9-11-19(12-10-18)22(25)26/h5,7-12,20H,3-4,6,13-16H2,1-2H3,(H,25,26)/b8-5+,17-7+/t20-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	134	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
EMD Serono Research Institute Curated by ChEMBL					Assay Description Displacement of [3H]PGE2 from human EP2 receptor expressed in HEK293 cells				Bioorg Med Chem Lett 17: 4323-7 (2007) Article DOI: 10.1016/j.bmcl.2007.05.025 BindingDB Entry DOI: 10.7270/Q2RF5VVC
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP4 subtype (Homo sapiens (Human))	BDBM50213975 (4-(2-((R)-2-(4-methylocta-1,3-dienyl)-5-oxopyrroli...) Show SMILES CCCC\C(C)=C\C=C\[C@H]1CCC(=O)N1CCc1ccc(cc1)C(O)=O Show InChI InChI=1S/C22H29NO3/c1-3-4-6-17(2)7-5-8-20-13-14-21(24)23(20)16-15-18-9-11-19(12-10-18)22(25)26/h5,7-12,20H,3-4,6,13-16H2,1-2H3,(H,25,26)/b8-5+,17-7+/t20-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	181	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
EMD Serono Research Institute Curated by ChEMBL					Assay Description Displacement of [3H]PGE2 from human EP4 receptor expressed in HEK293 cells				Bioorg Med Chem Lett 17: 4323-7 (2007) Article DOI: 10.1016/j.bmcl.2007.05.025 BindingDB Entry DOI: 10.7270/Q2RF5VVC
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP1 subtype (EP1) (Homo sapiens (Human))	BDBM50213975 (4-(2-((R)-2-(4-methylocta-1,3-dienyl)-5-oxopyrroli...) Show SMILES CCCC\C(C)=C\C=C\[C@H]1CCC(=O)N1CCc1ccc(cc1)C(O)=O Show InChI InChI=1S/C22H29NO3/c1-3-4-6-17(2)7-5-8-20-13-14-21(24)23(20)16-15-18-9-11-19(12-10-18)22(25)26/h5,7-12,20H,3-4,6,13-16H2,1-2H3,(H,25,26)/b8-5+,17-7+/t20-/m0/s1	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
EMD Serono Research Institute Curated by ChEMBL					Assay Description Displacement of [3H]PGE2 from human EP1 receptor expressed in HEK293 cells				Bioorg Med Chem Lett 17: 4323-7 (2007) Article DOI: 10.1016/j.bmcl.2007.05.025 BindingDB Entry DOI: 10.7270/Q2RF5VVC
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor (Homo sapiens (Human))	BDBM50213975 (4-(2-((R)-2-(4-methylocta-1,3-dienyl)-5-oxopyrroli...) Show SMILES CCCC\C(C)=C\C=C\[C@H]1CCC(=O)N1CCc1ccc(cc1)C(O)=O Show InChI InChI=1S/C22H29NO3/c1-3-4-6-17(2)7-5-8-20-13-14-21(24)23(20)16-15-18-9-11-19(12-10-18)22(25)26/h5,7-12,20H,3-4,6,13-16H2,1-2H3,(H,25,26)/b8-5+,17-7+/t20-/m0/s1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
EMD Serono Research Institute Curated by ChEMBL					Assay Description Displacement of [3H]PGE2 from human EP3 receptor expressed in HEK293 cells				Bioorg Med Chem Lett 17: 4323-7 (2007) Article DOI: 10.1016/j.bmcl.2007.05.025 BindingDB Entry DOI: 10.7270/Q2RF5VVC
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP4 subtype (Homo sapiens (Human))	BDBM50213975 (4-(2-((R)-2-(4-methylocta-1,3-dienyl)-5-oxopyrroli...) Show SMILES CCCC\C(C)=C\C=C\[C@H]1CCC(=O)N1CCc1ccc(cc1)C(O)=O Show InChI InChI=1S/C22H29NO3/c1-3-4-6-17(2)7-5-8-20-13-14-21(24)23(20)16-15-18-9-11-19(12-10-18)22(25)26/h5,7-12,20H,3-4,6,13-16H2,1-2H3,(H,25,26)/b8-5+,17-7+/t20-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	15	n/a	n/a	n/a	n/a
EMD Serono Research Institute Curated by ChEMBL					Assay Description Agonist activity at EP4 receptor expressed in HEK293 cells assessed as cAMP accumulation				Bioorg Med Chem Lett 17: 4323-7 (2007) Article DOI: 10.1016/j.bmcl.2007.05.025 BindingDB Entry DOI: 10.7270/Q2RF5VVC
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP2 subtype (Homo sapiens (Human))	BDBM50213975 (4-(2-((R)-2-(4-methylocta-1,3-dienyl)-5-oxopyrroli...) Show SMILES CCCC\C(C)=C\C=C\[C@H]1CCC(=O)N1CCc1ccc(cc1)C(O)=O Show InChI InChI=1S/C22H29NO3/c1-3-4-6-17(2)7-5-8-20-13-14-21(24)23(20)16-15-18-9-11-19(12-10-18)22(25)26/h5,7-12,20H,3-4,6,13-16H2,1-2H3,(H,25,26)/b8-5+,17-7+/t20-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	222	n/a	n/a	n/a	n/a
EMD Serono Research Institute Curated by ChEMBL					Assay Description Agonist activity at EP2 receptor expressed in HEK293 cells assessed as cAMP accumulation				Bioorg Med Chem Lett 17: 4323-7 (2007) Article DOI: 10.1016/j.bmcl.2007.05.025 BindingDB Entry DOI: 10.7270/Q2RF5VVC
					More data for this Ligand-Target Pair