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SMILES: COc1cc2CCN(C)[C@@H]3Cc4ccc(C)c(O)c4-c(c1)c23

InChI Key: InChIKey=UHYZEOGGPBAXJR-MRXNPFEDSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50214522   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50214522 ((R)-2-methoxy-6,10-dimethyl-5,6,6a,7-tetrahydro-4H...) Show SMILES COc1cc2CCN(C)[C@@H]3Cc4ccc(C)c(O)c4-c(c1)c23 Show InChI InChI=1S/C19H21NO2/c1-11-4-5-12-9-16-17-13(6-7-20(16)2)8-14(22-3)10-15(17)18(12)19(11)21/h4-5,8,10,16,21H,6-7,9H2,1-3H3/t16-/m1/s1	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	21.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Harvard Medical School Curated by ChEMBL					Assay Description Displacement of [3H]8-OH-DPAT from rat 5HT1A receptor				Bioorg Med Chem Lett 17: 4128-30 (2007) Article DOI: 10.1016/j.bmcl.2007.05.057 BindingDB Entry DOI: 10.7270/Q2ZG6RZ2
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Rattus norvegicus (rat))	BDBM50214522 ((R)-2-methoxy-6,10-dimethyl-5,6,6a,7-tetrahydro-4H...) Show SMILES COc1cc2CCN(C)[C@@H]3Cc4ccc(C)c(O)c4-c(c1)c23 Show InChI InChI=1S/C19H21NO2/c1-11-4-5-12-9-16-17-13(6-7-20(16)2)8-14(22-3)10-15(17)18(12)19(11)21/h4-5,8,10,16,21H,6-7,9H2,1-3H3/t16-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	271	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Harvard Medical School Curated by ChEMBL					Assay Description Displacement of [3H]ketanserin from rat 5HT2A receptor				Bioorg Med Chem Lett 17: 4128-30 (2007) Article DOI: 10.1016/j.bmcl.2007.05.057 BindingDB Entry DOI: 10.7270/Q2ZG6RZ2
					More data for this Ligand-Target Pair
D(1A) dopamine receptor (RAT)	BDBM50214522 ((R)-2-methoxy-6,10-dimethyl-5,6,6a,7-tetrahydro-4H...) Show SMILES COc1cc2CCN(C)[C@@H]3Cc4ccc(C)c(O)c4-c(c1)c23 Show InChI InChI=1S/C19H21NO2/c1-11-4-5-12-9-16-17-13(6-7-20(16)2)8-14(22-3)10-15(17)18(12)19(11)21/h4-5,8,10,16,21H,6-7,9H2,1-3H3/t16-/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.78E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Harvard Medical School Curated by ChEMBL					Assay Description Displacement of [3H]SCH23390 from rat dopamine D1 receptor				Bioorg Med Chem Lett 17: 4128-30 (2007) Article DOI: 10.1016/j.bmcl.2007.05.057 BindingDB Entry DOI: 10.7270/Q2ZG6RZ2
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50214522 ((R)-2-methoxy-6,10-dimethyl-5,6,6a,7-tetrahydro-4H...) Show SMILES COc1cc2CCN(C)[C@@H]3Cc4ccc(C)c(O)c4-c(c1)c23 Show InChI InChI=1S/C19H21NO2/c1-11-4-5-12-9-16-17-13(6-7-20(16)2)8-14(22-3)10-15(17)18(12)19(11)21/h4-5,8,10,16,21H,6-7,9H2,1-3H3/t16-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3.76E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Harvard Medical School Curated by ChEMBL					Assay Description Displacement of [3H]nemonapride from rat dopamine D2 receptor				Bioorg Med Chem Lett 17: 4128-30 (2007) Article DOI: 10.1016/j.bmcl.2007.05.057 BindingDB Entry DOI: 10.7270/Q2ZG6RZ2
					More data for this Ligand-Target Pair