BDBM50214728 2-(adamantan-1-ylamino)-1-[(S)-2-(5-methyl-[1,3,4]oxadiazole-2-carbonyl)-pyrrolidin-1-yl]-ethanone::CHEMBL232725

SMILES: Cc1nnc(o1)C(=O)[C@@H]1CCCN1C(=O)CNC12CC3CC(CC(C3)C1)C2

InChI Key: InChIKey=LNDZIFCFUWGUBW-OCABNYQQSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50214728   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Dipeptidyl peptidase 2 (DPP II) (Homo sapiens (Human))	BDBM50214728 (2-(adamantan-1-ylamino)-1-[(S)-2-(5-methyl-[1,3,4]...) Show SMILES Cc1nnc(o1)C(=O)[C@@H]1CCCN1C(=O)CNC12CC3CC(CC(C3)C1)C2 |TLB:16:17:20:24.23.22,THB:18:19:22:26.17.25,18:17:20.19.24:22,25:17:20:24.23.22,25:23:20:26.18.17| Show InChI InChI=1S/C20H28N4O3/c1-12-22-23-19(27-12)18(26)16-3-2-4-24(16)17(25)11-21-20-8-13-5-14(9-20)7-15(6-13)10-20/h13-16,21H,2-11H2,1H3/t13?,14?,15?,16-,20?/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.07E+3	n/a	n/a	n/a	n/a	n/a	n/a
LG Life Sciences, Ltd Curated by ChEMBL					Assay Description Inhibition of DPP2				Bioorg Med Chem Lett 17: 4167-72 (2007) Article DOI: 10.1016/j.bmcl.2007.05.046 BindingDB Entry DOI: 10.7270/Q2611006
					More data for this Ligand-Target Pair
Dipeptidyl peptidase VIII (Homo sapiens (Human))	BDBM50214728 (2-(adamantan-1-ylamino)-1-[(S)-2-(5-methyl-[1,3,4]...) Show SMILES Cc1nnc(o1)C(=O)[C@@H]1CCCN1C(=O)CNC12CC3CC(CC(C3)C1)C2 |TLB:16:17:20:24.23.22,THB:18:19:22:26.17.25,18:17:20.19.24:22,25:17:20:24.23.22,25:23:20:26.18.17| Show InChI InChI=1S/C20H28N4O3/c1-12-22-23-19(27-12)18(26)16-3-2-4-24(16)17(25)11-21-20-8-13-5-14(9-20)7-15(6-13)10-20/h13-16,21H,2-11H2,1H3/t13?,14?,15?,16-,20?/m0/s1	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	808	n/a	n/a	n/a	n/a	n/a	n/a
LG Life Sciences, Ltd Curated by ChEMBL					Assay Description Inhibition of DPP8				Bioorg Med Chem Lett 17: 4167-72 (2007) Article DOI: 10.1016/j.bmcl.2007.05.046 BindingDB Entry DOI: 10.7270/Q2611006
					More data for this Ligand-Target Pair
Dipeptidyl peptidase 4 (Homo sapiens (Human))	BDBM50214728 (2-(adamantan-1-ylamino)-1-[(S)-2-(5-methyl-[1,3,4]...) Show SMILES Cc1nnc(o1)C(=O)[C@@H]1CCCN1C(=O)CNC12CC3CC(CC(C3)C1)C2 |TLB:16:17:20:24.23.22,THB:18:19:22:26.17.25,18:17:20.19.24:22,25:17:20:24.23.22,25:23:20:26.18.17| Show InChI InChI=1S/C20H28N4O3/c1-12-22-23-19(27-12)18(26)16-3-2-4-24(16)17(25)11-21-20-8-13-5-14(9-20)7-15(6-13)10-20/h13-16,21H,2-11H2,1H3/t13?,14?,15?,16-,20?/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	84	n/a	n/a	n/a	n/a	n/a	n/a
LG Life Sciences, Ltd Curated by ChEMBL					Assay Description Inhibition of human DPP4				Bioorg Med Chem Lett 17: 4167-72 (2007) Article DOI: 10.1016/j.bmcl.2007.05.046 BindingDB Entry DOI: 10.7270/Q2611006
					More data for this Ligand-Target Pair