BDBM50214886 2-(3-(((5-methylbenzo[d]oxazol-2-yl)(3-phenoxypropyl)amino)methyl)phenoxy)butanoic acid::CHEMBL245465
SMILES: CCC(Oc1cccc(CN(CCCOc2ccccc2)c2nc3cc(C)ccc3o2)c1)C(O)=O
InChI Key: InChIKey=JHVLXXITSNQNAT-UHFFFAOYSA-N
Data: 3 EC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Peroxisome proliferator-activated receptor (Homo sapiens (Human)) | BDBM50214886![]() (2-(3-(((5-methylbenzo[d]oxazol-2-yl)(3-phenoxyprop...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a |
Kowa Co. Curated by ChEMBL | Assay Description Agonist activity at human recombinant PPARgamma by GAL4 transactivation assay | Bioorg Med Chem Lett 17: 4689-93 (2007) Article DOI: 10.1016/j.bmcl.2007.05.066 BindingDB Entry DOI: 10.7270/Q2J67GM5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Peroxisome proliferator-activated receptor alpha (PPAR alpha) (Homo sapiens (Human)) | BDBM50214886![]() (2-(3-(((5-methylbenzo[d]oxazol-2-yl)(3-phenoxyprop...) | PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 100 | n/a | n/a | n/a | n/a |
Kowa Co. Curated by ChEMBL | Assay Description Agonist activity at human recombinant PPARalpha by GAL4 transactivation assay | Bioorg Med Chem Lett 17: 4689-93 (2007) Article DOI: 10.1016/j.bmcl.2007.05.066 BindingDB Entry DOI: 10.7270/Q2J67GM5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Peroxisome proliferator-activated receptor delta (Homo sapiens (Human)) | BDBM50214886![]() (2-(3-(((5-methylbenzo[d]oxazol-2-yl)(3-phenoxyprop...) | PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 5.00E+3 | n/a | n/a | n/a | n/a |
Kowa Co. Curated by ChEMBL | Assay Description Agonist activity at human recombinant PPARdelta by GAL4 transactivation assay | Bioorg Med Chem Lett 17: 4689-93 (2007) Article DOI: 10.1016/j.bmcl.2007.05.066 BindingDB Entry DOI: 10.7270/Q2J67GM5 | |||||||||||
More data for this Ligand-Target Pair |