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SMILES: CN(CCn1c(=O)c2CN(Cc3ccc(C)cc3C)CCc2n(Cc2c(F)cccc2F)c1=O)Cc1ccccn1

InChI Key: InChIKey=XGURAZVFVAKWSE-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50215188   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Gonadotropin-releasing hormone receptor


(Homo sapiens (Human))		BDBM50215188
PNG
(6-(2,4-dimethylbenzyl)-1-(2,6-difluorobenzyl)-3-(2...)
Show SMILES CN(CCn1c(=O)c2CN(Cc3ccc(C)cc3C)CCc2n(Cc2c(F)cccc2F)c1=O)Cc1ccccn1
Show InChI InChI=1S/C32H35F2N5O2/c1-22-10-11-24(23(2)17-22)18-37-14-12-30-27(20-37)31(40)38(16-15-36(3)19-25-7-4-5-13-35-25)32(41)39(30)21-26-28(33)8-6-9-29(26)34/h4-11,13,17H,12,14-16,18-21H2,1-3H3
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Similars
Article
PubMed
 180n/an/an/an/an/an/an/an/a



Neurocrine Biosciences

Curated by ChEMBL


Assay Description
Displacement of [125I-His5,D-Tyr6]GnRH from human cloned GnRH receptor transfected in COS7 cells

Bioorg Med Chem 15: 5590-603 (2007)


Article DOI: 10.1016/j.bmc.2007.05.029
BindingDB Entry DOI: 10.7270/Q2VH5NJG
More data for this
Ligand-Target Pair