BDBM50215869 CHEMBL301781

SMILES: O[C@@H]1[C@@H](Cc2ccc(F)cc2)COc2cc(ccc12)-c1cc(Cl)ccc1C(O)=O

InChI Key: InChIKey=TVTQKPUMYOYZPC-OYHNWAKOSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50215869   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Leukotriene B4 receptor 1/2 (Homo sapiens (Human))	BDBM50215869 (CHEMBL301781) Show SMILES O[C@@H]1[C@@H](Cc2ccc(F)cc2)COc2cc(ccc12)-c1cc(Cl)ccc1C(O)=O Show InChI InChI=1S/C23H18ClFO4/c24-16-4-8-18(23(27)28)20(11-16)14-3-7-19-21(10-14)29-12-15(22(19)26)9-13-1-5-17(25)6-2-13/h1-8,10-11,15,22,26H,9,12H2,(H,27,28)/t15-,22+/m0/s1	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	54	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc Curated by ChEMBL					Assay Description Ability to inhibit LTB4 binding to LTB receptors on isolated human neutrophils.				Bioorg Med Chem Lett 8: 1781-6 (1998) BindingDB Entry DOI: 10.7270/Q2RR21F1
					More data for this Ligand-Target Pair
Leukotriene B4 receptor 1/2 (Homo sapiens (Human))	BDBM50215869 (CHEMBL301781) Show SMILES O[C@@H]1[C@@H](Cc2ccc(F)cc2)COc2cc(ccc12)-c1cc(Cl)ccc1C(O)=O Show InChI InChI=1S/C23H18ClFO4/c24-16-4-8-18(23(27)28)20(11-16)14-3-7-19-21(10-14)29-12-15(22(19)26)9-13-1-5-17(25)6-2-13/h1-8,10-11,15,22,26H,9,12H2,(H,27,28)/t15-,22+/m0/s1	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	400	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc Curated by ChEMBL					Assay Description Ability to inhibit LTB4-induced chemotaxis of isolated human neutrophils.				Bioorg Med Chem Lett 8: 1781-6 (1998) BindingDB Entry DOI: 10.7270/Q2RR21F1
					More data for this Ligand-Target Pair