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SMILES: COc1ccc(cc1OC)C(CC#N)N1C(=O)c2ccccc2C1=O

InChI Key: InChIKey=JXUXUNROSFVHQZ-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50216295   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
cAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D


(Homo sapiens (Human))		BDBM50216295
PNG
(CHEMBL314759)
Show SMILES COc1ccc(cc1OC)C(CC#N)N1C(=O)c2ccccc2C1=O
Show InChI InChI=1S/C19H16N2O4/c1-24-16-8-7-12(11-17(16)25-2)15(9-10-20)21-18(22)13-5-3-4-6-14(13)19(21)23/h3-8,11,15H,9H2,1-2H3
PDB

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antibodypedia
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CHEMBL
PC cid
PC sid
UniChem

Similars
PubMed
n/an/a 1.30E+3n/an/an/an/an/an/a



Celgene Corporation

Curated by ChEMBL


Assay Description
Inhibition of PDE4 enzyme from U937 cells

Bioorg Med Chem Lett 8: 2669-74 (1998)


BindingDB Entry DOI: 10.7270/Q2BK1FJH
More data for this
Ligand-Target Pair